Names | |
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Preferred IUPAC name
(1S,2R,5R)-5-(6-Amino-9H-purin-9-yl)-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol | |
Identifiers | |
3D model (JSmol)
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ChemSpider | |
ECHA InfoCard | 100.224.238 |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C12H14N4O3 | |
Molar mass | 262.265 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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3-Deazaneplanocin A (DZNep, C-c3Ado) is a drug which acts as both a S-adenosylhomocysteine synthesis inhibitor and also a histone methyltransferase EZH2 inhibitor. Studies have shown that it has effects in vitro against a variety of different tumor cell lines.[1][2][3][4][5]
In studies on mice, the drug was also found to be effective for the treatment of Ebola virus disease,[6] apparently interfering with the Ebola viruses ability to block interferon production, thus restoring the ability of immune system to rid the body of ebolavirus.[7][8]
Ebolavirus |
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Marburgvirus |
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Cuevavirus |
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Dianlovirus |
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Striavirus |
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Thamnovirus |
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