Adam Philip Geballe | |
|---|---|
| Born | 1951 (age 72–73) |
| Nationality | American |
| Parent(s) | Frances Koshland Geballe Theodore H. Geballe |
Adam P. Geballe is an American microbiologist and an Elected Fellow of the American Association for the Advancement of Science. Currently, he is a Professor[ambiguous] at University of Washington, an investigator at Fred Hutchinson Cancer Research Center, and a physician at Seattle Cancer Care Alliance.[1]
Geballe is the son of Frances "Sissy" (née Koshland) and Theodore H. Geballe.[2] His father is a physicist and his mother is the daughter of Daniel E. Koshland Sr. of the Haas family, owners of Levi Strauss & Co.[2] He has five siblings: Gordon Theodore Geballe, Alison Frances Geballe, Monica Thompson, Jennifer Geballe Norman, and Ernest Henry Geballe.[2] He earned his B.A. at Stanford University and his M.D. at Duke University.[3]
Adam Geballe's research has primarily focused on the mechanisms used by human cytomegalovirus to evade the host immune response. In particular, his group has identified and characterized the process by which the viral proteins pTRS1 and pIRS1 interfere with the host sensing of RNA mediated by the sensor PKR.[3][4] Additionally, his group researches poxvirus evasion of host immune responses, as well as various aspects of how viruses interact with host translational machinery.[5] His most cited paper is Upstream open reading frames as regulators of mRNA translation,[6][7]