Amphinase | |||||||
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Identifiers | |||||||
Organism | |||||||
Symbol | n/a | ||||||
PDB | 2P7S | ||||||
UniProt | P85073 | ||||||
Other data | |||||||
EC number | 3.1.27 | ||||||
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Amphinase is a ribonuclease enzyme found in the oocytes of the Northern leopard frog (Rana pipiens). Amphinase is a member of the pancreatic ribonuclease protein superfamily and degrades long RNA substrates.[2] Along with ranpirnase, another leopard frog ribonuclease, amphinase has been studied as a potential cancer therapy due to its unusual mechanism of cytotoxicity tested against tumor cells.[3]