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Names | |
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Preferred IUPAC name
(6Z,9Z,12Z,15Z)-1,1,1-Trifluorohenicosa-6,9,12,15-teraen-2-one | |
Other names
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Identifiers | |
3D model (JSmol)
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ChemSpider | |
PubChem CID
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UNII | |
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Properties | |
C21H31F3O | |
Molar mass | 356.473 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Arachidonyl trifluoromethyl ketone (ATK) is an analog of arachidonic acid.[1] that inhibits some isoforms of the enzyme phospholipase A2.[2] Specifically it inhibits the 85 kDa cystolic PLA2 (cPLA2).[2]
It has been studied as a neuroprotective agent after spinal cord injury,[2][3] and in animal models of multiple sclerosis.[4]