Cangzhou or Cang Prefecture (Chinese: 滄州) was a zhou (prefecture) in imperial China, centering on modern Cang County, Hebei, China. It existed (intermittently) from 517 until 1913.

The modern prefectural-level city Cangzhou, created in 1961, retains its name.

The administrative region of Cang Prefecture in the Tang dynasty is in modern eastern Hebei, the area sandwiched between Tianjin and northern Shandong. It probably includes parts of modern:

• Under the administration of Cangzhou, Hebei:
  • Cangzhou
  • Cang County
  • Botou
  • Qing County
  • Huanghua
  • Haixing County
  • Mengcun Hui Autonomous County
  • Yanshan County
  • Nanpi County
• Under the administration of Tianjin:
  • Tianjin
• Under the administration of Binzhou, Shandong:
  • Wudi County
• Under the administration of Dezhou, Shandong:
  • Leling
  • Ningjin County
  • Qingyun County

• Shi Weile, ed. (2005). Zhongguo Lishi Diming Da Cidian (中国历史地名大词典) [Large Dictionary of Chinese Historical Place Names] (in Chinese). China Social Sciences Press. p. 1343. ISBN 7-5004-4929-1.