This article needs more reliable medical references for verification or relies too heavily on primary sources. Please review the contents of the article and add the appropriate references if you can. Unsourced or poorly sourced material may be challenged and removed. Find sources: "Cannabigerovarin" – news · newspapers · books · scholar · JSTOR (March 2022)
Cannabigerovarin
Names
IUPAC name
2-[(2E)-3,7-dimethylocta-2,6-dienyl]-5-propylbenzene-1,3-diol
Other names
Cannabigerovarol
CBGV
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C19H28O2/c1-5-7-16-12-18(20)17(19(21)13-16)11-10-15(4)9-6-8-14(2)3/h8,10,12-13,20-21H,5-7,9,11H2,1-4H3/b15-10+
  • CCCC1=CC(=C(C(=C1)O)C/C=C(\C)/CCC=C(C)C)O
Properties
C19H28O2
Molar mass 288.431 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Cannabigerovarin (CBGV), the propyl homolog of cannabigerol (CBG), is a cannabinoid present in Cannabis.[1][2][3][4] There is no observation related to the psychoactive or psychotropic effects of CBGV when consumed or inhaled.[5][1] The possible benefits of cannabigerovarin in human bodies are painkilling and anti-inflammatory properties to treat conditions like fibromyalgia and arthritis, the treatment and improvement of the dry-skin syndrome, cancer treatment by reducing the growth of cancer cells in patients who have leukemia.[6][5][7][8][9] According to the pain-relieving effects of this natural cannabinoid, it can be helpful to treat patients who were undergoing drug exposure like chemotherapy or radiation therapy.[10][9] In addition, cannabigerol metabolism increases and has a better absorption from the body when paired with cannabigerovarin.[11]

References

  1. ^ a b Tolomeo, Francesco; Russo, Fabiana; Vandelli, Maria Angela; Biagini, Giuseppe; Capriotti, Anna Laura; Laganà, Aldo; Carbone, Luigi; Gigli, Giuseppe; Cannazza, Giuseppe; Citti, Cinzia (September 2021). "HPLC–UV–HRMS analysis of cannabigerovarin and cannabigerobutol, the two impurities of cannabigerol extracted from hemp". Journal of Pharmaceutical and Biomedical Analysis. 203: 114215. doi:10.1016/j.jpba.2021.114215. ISSN 0731-7085. PMID 34153935.
  2. ^ "What is Cannabigerovarin (CBGV)?". Marijuana Doctors | Online Medical Card Directory. Retrieved 2021-11-24.
  3. ^ Hillig, Karl W.; Mahlberg, Paul G. (2004). "A chemotaxonomic analysis of cannabinoid variation in Cannabis (Cannabaceae)". American Journal of Botany. 91 (6): 966–975. doi:10.3732/ajb.91.6.966. ISSN 1537-2197. PMID 21653452. S2CID 32469533.
  4. ^ de Meijer, E. P. M.; Hammond, K. M.; Micheler, M. (2009-01-01). "The inheritance of chemical phenotype in Cannabis sativa L. (III): variation in cannabichromene proportion". Euphytica. 165 (2): 293–311. doi:10.1007/s10681-008-9787-1. ISSN 1573-5060. S2CID 24132168.
  5. ^ a b Oláh, Attila; Markovics, Arnold; Szabó-Papp, Judit; Szabó, Pálma Tímea; Stott, Colin; Zouboulis, Christos C.; Bíró, Tamás (September 2016). "Differential effectiveness of selected non-psychotropic phytocannabinoids on human sebocyte functions implicates their introduction in dry/seborrhoeic skin and acne treatment". Experimental Dermatology. 25 (9): 701–707. doi:10.1111/exd.13042. hdl:2437/243742. PMID 27094344. S2CID 39290296.
  6. ^ Chakravarti, Bandana; Ravi, Janani; Ganju, Ramesh K. (2014-07-17). "Cannabinoids as therapeutic agents in cancer: current status and future implications". Oncotarget. 5 (15): 5852–5872. doi:10.18632/oncotarget.2233. ISSN 1949-2553. PMC 4171598. PMID 25115386.
  7. ^ Burstein, Sumner (April 2015). "Cannabidiol (CBD) and its analogs: a review of their effects on inflammation". Bioorganic & Medicinal Chemistry. 23 (7): 1377–1385. doi:10.1016/j.bmc.2015.01.059. ISSN 0968-0896. PMID 25703248.
  8. ^ Grof, Christopher P. L. (2018-05-24). "Cannabis, from plant to pill". British Journal of Clinical Pharmacology. 84 (11): 2463–2467. doi:10.1111/bcp.13618. ISSN 0306-5251. PMC 6177712. PMID 29701252.
  9. ^ a b Alsen, Mathilda; Sinclair, Catherine; Cooke, Peter; Ziadkhanpour, Kimia; Genden, Eric; van Gerwen, Maaike (2021-01-19). "Endocrine Disrupting Chemicals and Thyroid Cancer: An Overview". Toxics. 9 (1): 14. doi:10.3390/toxics9010014. ISSN 2305-6304. PMC 7832870. PMID 33477829.
  10. ^ "What is CBGV?". Botany Farms. 2020-09-25. Retrieved 2021-11-24.
  11. ^ de Meijer, E. P. M.; Hammond, K. M. (September 2005). "The inheritance of chemical phenotype in Cannabis sativa L. (II): Cannabigerol predominant plants". Euphytica. 145 (1–2): 189–198. doi:10.1007/s10681-005-1164-8. ISSN 0014-2336. S2CID 13496446.
Categories