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Casimir Pfyffer von Altishofen (10 October 1794, in Rome – 11 November 1875) was a Swiss politician and jurist. He was mayor of Lucerne (1832–1835), President of the Swiss National Council (1854/1855) and five times President of the Federal Supreme Court.
Kasimir-Pfyffer-Strasse in Lucerne is named for him.
