Dominic Kwiatkowski | |
---|---|
Born | Dominic P. Kwiatkowski 25 May 1953 Hammersmith, London, England |
Died | 27 April 2023 | (aged 69)
Scientific career | |
Fields | Genomics Malaria[1][2] |
Institutions | Wellcome Sanger Institute University of Cambridge University of Oxford Guy's Hospital Leyland Motors[3] |
Website | sanger |
Dominic Kwiatkowski FRS FMedSci FRCP[4][5] (25 May 1953 – 27 April 2023) was an English medical researcher and geneticist who was head of the parasites and microbes programme at the Wellcome Sanger Institute[3] in Cambridge and a Professor of Genomics at the University of Oxford.[4] Kwiatkowski applied genomics and computational analysis to problems in infectious disease, with the aim of finding ways to reduce the burden of disease in the developing world.[4][6][7][8]
Kwiatkowski trained as a paediatrician at Guy's Hospital[when?] in London.[4]
Kwiatkowski spent several years in West Africa, where malaria causes high levels of infant mortality, and this was a major focus of his research over the past thirty years.[4] He made significant contributions to the understanding of malaria pathogenesis and genetic mechanisms of resistance to the disease.[4] He also pioneered genome-wide association studies (GWAS) in Africa and led large international collaborations to characterise the genomic diversity of parasite and mosquito populations around the world.[4] This work is yielding deep insights into the evolutionary biology of drug resistance and pesticide resistance with practical implications for disease control.[4]
In 2005 Kwiatkowski founded a data-sharing network, MalariaGEN, which has fostered productive research collaborations in more than forty malaria endemic countries, and has become a model for equitable sharing of genetic data and research capacity building in resource-poor settings.[4][1]
Kwiatkowski died on 27 April 2023, at the age of 69.[9]
Kwiatkowski was elected a Fellow of the Royal Society (FRS) in 2018[4] and a Fellow of the Academy of Medical Sciences (FMedSci) in 2000.[10]
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