List of examples of in vivo transdifferentiation through transfection
A list of examples of in vivo transdifferentiation through transfection:[1]
- mouse hepatocytes → B cells (Pdx1)[2]
- exocrine cells → B cells (Pdx1, Ngn3, and v-maf musculoaponeurotic fibrosarcoma oncogene family protein A)[3]
- nonsensory cells → inner hair cells (Atoh1 and MathI)[4]
- non cardiogenic mesoderm → cardiomyocytes (Gata4, Tbx5 and Smarcd3 or Baf60c)[5]
Through excision:
- B-cell precursors → hematopoietic progenitors(-Pax5)[6]
- In adult ovarian follicles, granulosa and thecal cells → functional Sertoli-like and Leydig-like cells (-Foxl1)[7]