Fc receptor-like molecules (FCRLs) are a class of proteins that resemble Fc receptors. They have been characterized in a number of species, including humans and mice. They are preferentially expressed by B lymphocytes. Unlike the classical Fc receptors, there is no strong evidence that suggests that FCRLs bind to the Fc portion of antibodies. Their function is unknown.[1]
It has been indicated that FCRLs may be a unique marker for immune cells in the brain called microglia, compared to other CNS cells and peripheral immune cells.[2]