Her laboratory carried out the first systematic inactivation of the majority of genes in an animal through constructing and screening a genome-wide RNA interference library for the nematode C. elegans.[13] Ahringer studies the control of gene expression and genome architecture in development, using C. elegans as a model system.[14]
Ahringer became a group leader in the Department of Genetics in Cambridge in 1996, then moved to the Gurdon Institute in 1998.[21] Her laboratory carried out the first systematic inactivation of the majority of genes in any animal by constructing and screening a genome-wide RNAi library for Caenorhabditis elegans (C. elegans). Ahringer's research group studies the regulation of chromatin structure and function in gene expression and genome organization using the nematode C. elegans as a model to understand development and disease. The Ahringer Lab research is funded by the Wellcome Trust.[8]
^Kamath, R.; Fraser, A.; Dong, Y.; Poulin, G.; Durbin, R.; Gotta, M.; Kanapin, A.; Le Bot, N.; Moreno, S.; Sohrmann, M.; Welchman, D. P.; Zipperlen, P.; Ahringer, J. (2003). "Systematic functional analysis of the Caenorhabditis elegans genome using RNAi". Nature. 421 (6920): 231–237. doi:10.1038/nature01278. PMID12529635.
^Ahringer, J.; Kamath, A. G.; Zipperlen, R. S.; Martinez-Campos, P.; Sohrmann, M.; Ahringer, M. (2000). "Functional genomic analysis of C. Elegans chromosome I by systematic RNA interference". Nature. 408 (6810): 325–330. doi:10.1038/35042517. PMID11099033.
^Murphy, C. T.; McCarroll, S. A.; Bargmann, C. I.; Fraser, A.; Kamath, R. S.; Ahringer, J.; Li, H.; Kenyon, C. (2003). "Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans". Nature. 424 (6946): 277–283. doi:10.1038/nature01789. PMID12845331.
^Ashrafi, K.; Chang, F. Y.; Watts, J. L.; Fraser, A. G.; Kamath, R. S.; Ahringer, J.; Ruvkun, G. (2003). "Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes". Nature. 421 (6920): 268–272. doi:10.1038/nature01279. PMID12529643.
^Lee, S. S.; Lee, R. Y. N.; Fraser, A. G.; Kamath, R. S.; Ahringer, J.; Ruvkun, G. (2002). "A systematic RNAi screen identifies a critical role for mitochondria in C. Elegans longevity". Nature Genetics. 33 (1): 40–48. doi:10.1038/ng1056. PMID12447374.
^ abcFlorence Leroy based on Custom Repute template. "Home | Ahringer Lab". Gurdon.cam.ac.uk. Archived from the original on 2016-10-17. Retrieved 2016-12-19.
^Pocock, R.; Ahringer, J.; Mitsch, M.; Maxwell, S.; Woollard, A. (2004). "A regulatory network of T-box genes and the even-skipped homologue vab-7 controls patterning and morphogenesis in C. Elegans". Development. 131 (10): 2373–2385. doi:10.1242/dev.01110. PMID15102704.
^Ahringer, Julie Ann (1991). Posttranscriptional regulation offem-3, a sex-determining gene of Caenorhabditis elegans (PhD thesis). University of Wisconsin–Madison. ProQuest303972449.
^Ahringer, J.; Kimble, J. (1991). "Control of the sperm–oocyte switch in Caenorhabditis elegans hermaphrodites by the fem-3 3′ untranslated region". Nature. 349 (6307): 346–348. doi:10.1038/349346a0. PMID1702880.
^Malone, C. J.; Misner, L.; Le Bot, N.; Tsai, M. C.; Campbell, J. M.; Ahringer, J.; White, J. G. (2003). "The C. Elegans hook protein, ZYG-12, mediates the essential attachment between the centrosome and nucleus". Cell. 115 (7): 825–836. doi:10.1016/S0092-8674(03)00985-1. PMID14697201.