Many microcomputer makes and models could run some version or derivation of the CP/M disk operating system. Eight-bit computers running CP/M 80 were built around an Intel 8080/8085, Zilog Z80, or compatible CPU. CP/M 86 ran on the Intel 8086 and 8088. Some computers were suitable for CP/M as delivered. Others needed hardware modifications such as a memory expansion or modification, new boot ROMs, or the addition of a floppy disk drive. A few very popular home computers using processors not supported by CP/M had plug-in Z80 or compatible processors, allowing them to use CP/M and retaining the base machine's keyboard, peripherals, and sometimes video display and memory.

The following is an alphabetical list of some computers running CP/M.

A

• Ai Electronics ABC-24 / ABC-26 (Japan, running Dosket, CP/M & M/PM)
• Action Computer Enterprise ACE-1000
• Action Computer Enterprise Discovery D-500 (CP/M-80 on each of up to 4 user processors, DPC/OS on service processor)
• Action Computer Enterprise Discovery D-1600 (CP/M-80 on each of up to 15 user processors, DPC/OS on service processor)
• Actrix Computer Corp. Actrix (Access Matrix)
• Advanced Digital Corporation Super Six
• Allen Bradley Advisor - Industrial Programmable controller graphical user interface (development mode only), fl. ca. 1985
• Alspa
• MITS Altair 8800
• Altos 580
• Amada Aries 222/245 CNC turret punch press
• Amstrad CPC 464^[1] (w/DDI-1 disk drive interface), 664, 6128, 6128Plus
• Amstrad PCW 8256/8512/9512/9256/10
• Amust Executive 816
• Apple II (with a Z-80 card like the Microsoft SoftCard; on some clones a SoftCard equivalent was built into the mainboard)
• Apple III (with a Z-80 card like the Apple SoftCard III)^[2][3]
• Applied Technology MicroBee (56KB+ RAM models)
• Aster CT-80
• Atari 800 and XL/XE (with ATR8000 module, LDW Super 2000, CA-2001 or Indus GT disk drives expanded to 64k)
• Atari ST - runs GEMDOS, which was DRI's more advanced replacement for CP/M for use with their GEM GUI
• ATM-turbo - Soviet/Russian clone of ZX-Spectrum with extension graphic and 512/1024Kb RAM: CP/M 2.2 in ROM
• AT&T 6300 with CPU 3 upgrade
• AT&T 6300 PLUS

B

• Basis 108^[4]
• BBC Micro (with external Z80 module)
• Beehive Topper II
• BMC if-800
• Bondwell II,12, 14
• BT Merlin M2215 series based on ICL PC-2 (CP/M) (also ran MP/M II+)
• BT Merlin M4000 series based on Logica Kennett (Concurrent CP/M-86)

C

• Camputers Lynx (96k/128k models)
• Casio FP1000 FL
• CASU Super-C - Z80 based with a 21 slot S100 bus (Networkable with MP/M) - UK manufactured
• CASU Mini-C - Z80 based with a 7 slot S100 bus and twin 8" floppy disk drives (Networkable with MP/M) - UK manufactured
• Challenger III - Ohio Scientific OSI-CP/M
• Cifer Systems 2684, 2887, 1887 - Melksham, England.^[5]
• CIP04 - Romanian computer
• CoBra - Romanian computer
• Coleco Adam (with a CP/M digital data pack)
• Comart Communicator (CP/M-80), C-Frame, K-Frame, Workstation and Quad (Concurrent CP/M-86)
• Commodore 64 (with Z80 plug-in cartridge)^[6]
• Commodore 128 (using its internal Z80 processor—along with its 8502—ran CP/M+ which supported memory paging)
• Compaq Portable - was available with CP/M as a factory installed option.
• Compis
• Compupro
• Cromemco
• C't180 HD64180 ECB-System (CP/M2.2 & 3.x)
• Cub-Z - Romanian made computer

D

• Datamax UV-1R
• Data Soft PCS 80 and VDP 80 (France, 1977)
• Data Technology Industries "Associate" (USA, 1982)
• DEC Rainbow 100/100+ (could run both CP/M and CP/M-86)
• DEC VT180 (aka Personal Computing Option, aka 'Robin')
• Digital Group DG1

E

• Eagle Computer Eagle I, II, III, IV, V
• ELWRO 800 Junior Polish clone of Sinclair ZX spectrum—running CP/J, a CP/M derivative with simple networking abilities
• ENER 1000
• Enterprise 128 (with EXDOS/IS-DOS extensions)
• Epic Episode
• Epson PX-4, PX-8 (Geneva), QX-10, QX-16
• Eracom ERA-50 & ERA-60 with encrypted disks (Eracom Corporation, Australia)
• Exidy Sorcerer

F

• Ferguson Big Board
• FK-1 - Czech microcomputer
• Franklin ACE 1000 (with Microsoft Z-80 SoftCard)
• Franklin ACE 1200 (includes a rebranded PCPI Appli-Card)
• Fujitsu Micro 7 (with Z-80 plug-in card)

G

• General Processor GPS5 (Italy, running CP/M 86 - Concurrent CP/M 86)
• General Processor Model T (Italy, 1980 running CP/M 80)
• Grundy NewBrain
• Genie II, IIs, III, IIIs
• Goupil G3
• G.Z.E. UNIMOR Bosman 8 (Poland, 1987 running CPM/R, CP/M 2.2 compatible)
• Gemini 801 and Gemini Galaxy (UK, 1981-1983 running CP/M 2.2 and MP/M)
• GNAT Computers (San Diego 1975-? CP/M 2.2 Industrial Control Systems, Sail Cutting and others)

H

• HBN Computer (Le) Guépard
• HC-88
• HC-2000
• Heath/Zenith Heathkit H90|H90 and Heathkit H89/Zenith Z-89
• Hewlett-Packard HP-85 / HP-87 (with addition of CP/M Module containing Z80)
• Hewlett-Packard HP-125 and HP-120, one Z80 each for CP/M and the inherent HP terminal
• Hobbit
• Holborn 6100
• Holborn 9100 (Netherlands, 1981)
• Husky Computers Ltd Hunter (1 and 2, 16), Hawk

I

• Ibex 7150 and other models
• ICL PC-1 (CP/M) (also ran MP/M)
• ICL PC-2 (CP/M) (also ran MP/M II+)
• ICL PC-16 (Concurrent CP/M-86)
• ICL PC Quattro (Concurrent CP/M-86)
• ICL DRS8801 (CP/M-86)
• ICL DRS300 (Concurrent CP/M-86)
• ICL DRS20 (CP/M or Concurrent CP/M-86)
• IBM Displaywriter^[7]
• IBM PC (CP/M-86 only; CP/M-80 with the Baby Blue Z-80 card)
• IMSAI 8080
• IMSAI VDP-80 (8085 3 MHz)
• Intel MDS-80
• Intertec Superbrain
• Iotec
• Iskra Delta Partner
• Itautec I-7000, I-7000G, I-7000 Jr. (SIM/M)
• ITT 3030
• Ivel Ultra

J

• JET-80 (Swedish Made Computer)
• Juku E5101–E5104 came with an adaptation of CP/M called EKDOS
• JUNIOR Romanian Computer

K

• Kaypro
• KC 85/2-4
• Kontron PSI98 (KOS & CP/M2.2)
• Korvet (Корвет) — Soviet PC

L

• Labtam
• LNW-80
• LOBO Max-80
• Logica VTS 2200 (CP/M-86)
• Logica VTS Kennet (Concurrent CP/M-86)
• LOS 25 (10 MB harddisc)
• Luxor ABC 802, ABC 806 (Sweden, 1981)

M

• MCP (128K, Z80, S-100 bus)
• MC CP/M Computer (Z80 ECB-System, CP/M2.2)
• Megatel Quark
• Memotech MTX
• MicroBee
• Micro Craft Dimension 68000 (CP/M-68K, and CP/M-80 with optional Z80 card)
• Micromation M/System, Mariner and MiSystem (MP/M and MP/M II)
• Micromint SB180 (Hitachi HD64180 CPU)
• Mikromeri Spectra Z (Finland)
• Morrow Designs (MD2, MD3, MD11)
• MSX (some MSX-standard machines ran the CP/M-like MSX-DOS)
• Mycron 3
• M 18 Romanian Computer
• M 118 Romanian Computer
• MK 45 Polish computer based on MCY7880

N

• N8VEM
• N8VEM ZetaSBC
• Nabu Network PC
• Nascom 1, 2
• NCR Decision Mate V
• NEC APC
• NEC PC-8001 Mk II
• NEC PC-8801
• Nelma Persona
• NorthStar Advantage (all in one computer)
• NorthStar Horizon (S-100)
• Nokia MikroMikko 1
• NYLAC Computers NYLAC (S-100)

O

• Ohio Scientific computers using the 510 triple-processor CPU board
• OKI IF-800 (Z80 5 MHz) Second Z80 on video controller
• Olivetti ETV300
• Olivetti M20 (CP/M-8000)
• Osborne 1
• Osborne Executive
• Osborne Vixen
• Otrona Attaché
• Otrona Attaché 8:16

P

• P112
• Philips P2000T
• Philips 3003/3004
• Piccolo RC-700|Piccolo^[8]
• Partner RC-750|Piccolo^[9]
• Piccoline RC-759^[10]
• Pied Piper^[11]
• PolyMorphic Systems 8813
• The Portable Computer Co (AU) PortaPak
• Profi - Soviet/Russian clone of ZX-Spectrum with extension grafic and 1024Kb RAM: CP/M plus in ROM
• Processor Technology Sol-20 (optional)
• Pulsars Little Big Board

Q

• Quasar Data Products QDP-300

R

• RAIR "Black Box" (also ran MP/M)
• Regnecentralen Piccolo RC-700
• Regnecentralen Piccoline RC-759
• Research Machines 380Z and LINK 480Z
• Retro! Z80 by John Winans
• Rex Computer Company REX 1
• Robotron A 5120
• Robotron KC 85, KC 87
• Robotron PC 1715
• Royal Business Machines 7000 "Friday"

S

• SAGE II / IV CP/M-68K
• SAM Coupé - (Pro-Dos = CP/M 2.2)
• Samsung SPC-1000
• Sanyo MBC families (i.e. MBC-1150)
• SBS 8000
• Scandis
• Seequa Chameleon
• Sharp MZ series
• Sharp X1 series
• Sirius 1 (sold in the U.S. as the Victor 9000)
• Software Publisher's ATR8000
• Sony SMC-70
• Sord M5 has CP/M as an option, CP/M-68K standard for the M68/M68MX
• Spectravideo SV-318/328
• Sperry Univac UTS 40 CP/M 2.2 - Zilog 80^[12]
• Stride 400 series CP/M-68K was one of many operating systems on these
• ZX Spectrum family (built by Amstrad)

T

• Tatung Einstein TC-01 (runs Xtal/DOS which is CP/M compatible)
• Tandy TRS-80
• Technical Design Labs (TDL) XITAN
• TeleData (Z80 Laptop)
• Telenova Compis (CP/M-86)
• Teleputer III
• Televideo TS-80x Series
• Televideo TS-160x Series
• TI-99/4A (with the MorningStar CP/M card or the Foundation CP/M card)
• Tiki-100 (runs KP/M, or later renamed TIKO. A CP/M 2.2 Clone.)
• TIM-011
• TIM-S Plus
• Timex FDD3000 (on Z80 CPU) with ZX Spectrum as terminal.
• Toshiba T100
• Toshiba T200
• Toshiba T200 C-5
• Toshiba T200 C-20
• Toshiba T250
• Transtec BC2
• Triumph-Adler AlphaTronic P1/P2
• Triumph-Adler AlphaTronic P3/P4
• Triumph-Adler AlphaTronic P30/P40
• Triumph-Adler AlphaTronic PC (CPU was a Hitachi Z80 clone)
• Tycom Microframe

U

• Unitron 8000, a dual processor machine built São Paulo in the early 1980s. The Unitron could boot either as an Apple II clone (using a clone 6502 processor) or in CP/M (using the Z80).

V

• Vector-06C (Intel 8080, 16 color graphics, made in USSR)
• Vector Graphic Vector Graphic Corporation Vector Model 1,2 (Internal Model),3, Model 4 (Z80 & 8088 CP/M, CP/M-86 & PCDOS), Model 10 (Multiuser)
• Victor 9000 (sold as the Sirius 1 in Europe)
• Video Technology Laser 500/700
• Visual Technology (Lowell, Ma) Visual 1050, 1100 (Not Released)

W

• Wave Mate Bullet
• Welect 80.2 (France, 1982)
• West PC-800

X

• Xerox 820
• Xerox Sunrise 1800 / 1805

Y

• Yodobashi Formula-1

Z

• Zenith Data Systems Z-89 (aka Heathkit H89)
• Zenith Data Systems Z-100 (CP/M-85)
• Zorba