Arts
- Derek Bell (1935–2002), harpist and composer
- Eric Bell (born 1947), guitarist; former member of Them and Thin Lizzy
- James Bingham (1925–2009), artist
- Doris Blair (born 1915), artist
- Kenneth Branagh (born 1960), actor and director
- Jake Burns (born 1958), musician (Stiff Little Fingers)
- Vivian Campbell (born 1962), musician (Dio, Def Leppard)
- Ciaran Carson (1948–2019), poet and novelist
- Catoan, band
- Nathan Connolly (born 1981), musician (Snow Patrol)
- Mairtín Crawford (1967–2004), poet
- Gerald Dawe (born 1952), poet
- Gerald Dillon (1916–1971), artist
- Laura Donnelly (born 1982), actress
- Jamie Dornan (born 1982), actor
- Barry Douglas (born 1960), concert pianist
- Garth Ennis (born 1970), comics writer
- Padraic Fiacc (1924–2019), poet
- Olga Fielden (1903–1973), playwright and novelist
- James Galway (born 1939), musician
- Joe Graham (1944–2021), writer and historian
- Stuart Graham (born 1967), actor
- Ceara Grehan, theatre and opera singer
- Karen Hassan (born 1981), actress
- Hector Heathwood (born 1957), photographer of erotica, fetish and burlesque
- Paul Henry (1876–1958), painter
- John Hewitt (1907–1987), poet
- Ciarán Hinds (born 1953), actor
- P.J. Holden (born 1969), comic artist
- David Holmes (born 1969), DJ
- Brian Desmond Hurst (1895–1986), film director
- Oliver Jeffers (born 1977), artist
- Brian Keenan (born 1950), hostage and writer
- Ian Knox (born 1943) comic artist and political cartoonist
- Sam Kydd (1915–1982), actor
- Ben Kyle (born 1981), musician, leader of Romantica
- Sir John Lavery (1856–1941), artist
- C.S. Lewis (1898–1963), author and scholar
- Michael Longley (born 1939), poet
- Ian Masterson, musician[1]
- Paul Masterson, music producer[2]
- Gerry McAvoy (born 1951), musician
- Christopher McCafferty, DJ, club promoter
- Gerard McCarthy (born 1981), actor and television presenter
- John McCrea (born 1966), comic artist
- Ian McDonald (born 1960), science fiction author
- Siobhán McKenna (1922–1986), actress
- Ali McMordie (born 1959), musician (Stiff Little Fingers)
- Katie Melua (born 1984), musician
- Seaneen Molloy, blogger and columnist[3]
- Brian Moore (1921–1999), novelist
- Gary Moore (1952–2011), musician, blues and rock guitarist formerly of Thin Lizzy
- Van Morisson (born 1945), musician
- Clara Mulholland (1849–1934), writer
- Ruby Murray (1935–1996), singer/actress
- Doc Neeson (1947–2014), musician
- Una O'Connor (1880–1959), actress
- Jonjo O'Neill (born 1952), actor
- Patricia Quinn (born 1944), actress in The Rocky Horror Picture Show
- Stephen Rea (born 1946), actor
- Bob Shaw, science fiction (1931–1996), author
- Duke Special (born 1971), musician
- Bronágh Taggart, actress
- Austin Trevor (1897–1978), actor
- Rachel Tucker (born 1981), actress (West End)
- And So I Watch You From Afar (formed 2005) Instrumental Math Rock Band
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