Medical condition
Lymphocytic meningoradiculitis Other names Bannwarth Syndrome
Lymphocytic meningoradiculitis , also known as Bannwarth syndrome , is a neurological disease characterized as intense nerve pain radiating from the spine.[ 1] The disease is caused by an infection of Borrelia burgdorferi , a tick-borne spirochete bacterium also responsible for causing Lyme disease .
Lymphocytic meningoradiculitis is characterized by an intense spinal pain in the lumbar and cervical regions, radiating to the extremities. Symptoms may include facial paralysis, abducens palsy , anorexia , tiredness, headache, double vision , paraesthesia , and erythema migrans .[ 2]
Lymphocytic meningoradiculitis is treated with antibiotics. Oral doxycycline or IV ceftriaxone are typically recommended for 14-21 days.[ 3] [ 4] [ 5]
The disease was first reported in 1941 by German neurologist, Alfred Bannwarth , who described the main symptoms as intense radicular pain, facial palsy, severe headaches, and vomiting.[ 6] A common feature he observed in his infected patients was an abnormal increase of lymphocytes in their cerebrospinal fluid (CSF).[citation needed ]
^ Hindfelt, B.; Jeppsson, P. G.; Nilsson, B.; Olsson, J. E.; Ryberg, B.; Sörnäs, R. (1982-10-01). "Clinical and cerebrospinal fluid findings in lymphocytic meningo-radiculitis (Bannwarth's syndrome)" . Acta Neurologica Scandinavica . 66 (4): 444–453. doi :10.1111/j.1600-0404.1982.tb06866.x . ISSN 0001-6314 . PMID 7148387 . S2CID 29270560 .
^ Ryberg, B. (1984-01-01). "Bannwarth's syndrome (lymphocytic meningoradiculitis) in Sweden" . The Yale Journal of Biology and Medicine . 57 (4): 499–503. ISSN 0044-0086 . PMC 2590032 . PMID 6516452 .
^ Mygland, A (2010). "EFNS guidelines on the diagnosis and management of European Lyme neuroborreliosis" . European Journal of Neurology . 17 (1): 8–e4. doi :10.1111/j.1468-1331.2009.02862.x . PMID 19930447 . S2CID 14166137 .
^ Rauer, Sebastian; et al. (27 February 2020). "Guidelines for diagnosis and treatment in neurology – Lyme neuroborreliosis" . GMS German Medical Science . 18 : Doc03. doi :10.3205/000279 . PMC 7174852 . PMID 32341686 .
^ Lantos, Paul M; et al. (23 January 2021). "Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA), American Academy of Neurology (AAN), and American College of Rheumatology (ACR): 2020 Guidelines for the Prevention, Diagnosis and Treatment of Lyme Disease" . Clinical Infectious Diseases . 72 (1): e1–e48. doi :10.1093/cid/ciaa1215 . PMID 33417672 .
^ Weber, Klaus; Burgdorfer, Willy (2012-12-06). Aspects of Lyme Borreliosis . Springer Science & Business Media. ISBN 9783642776144 .