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Phenylpiperazine
Skeletal formula of phenylpiperazine
Ball-and-stick model of the phenylpiperazine molecule
Names
Preferred IUPAC name
1-Phenylpiperazine
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.001.969 Edit this at Wikidata
UNII
  • InChI=1S/C10H14N2/c1-2-4-10(5-3-1)12-8-6-11-7-9-12/h1-5,11H,6-9H2 checkY
    Key: YZTJYBJCZXZGCT-UHFFFAOYSA-N checkY
  • c1cc(ccc1)N2CCNCC2
Properties
C10H14N2
Molar mass 162.23 g/mol
Appearance clear colourless to yellow liquid
Density 1.028g/cm3
Melting point 18.8 °C (65.8 °F; 291.9 K)
Boiling point 287.2 °C (549.0 °F; 560.3 K) at 760mmHg
insoluble
Hazards
Flash point 138.3 °C (280.9 °F; 411.4 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)

1-Phenylpiperazine is a simple chemical compound featuring a phenyl group bound to a piperazine ring. The suffix ‘-piprazole’ is sometimes used in the names of drugs to indicate they belong to this class.[1]

1-Phenylpiperazine is toxic, its oral LD50 in rats is 210 mg/kg.[2]

List phenylpiperazine derivatives

  1. Alpertine [27076-46-6]
  2. BP 554 [82900-57-0]
  3. Butropipazone [2354-61-2]
  4. CAM89 alluded to here: WO 2018102233 
  5. Centphenaquin [98459-16-6]
  6. Centpropazine [91315-34-3] [34675-77-9]
  7. Clodoxopone [71923-34-7]
  8. Dropropizine [17692-31-8]
  9. Etoperidone
  10. FAUC-299 [313972-96-2]
  11. FAUC-312 [562104-72-7]
  12. LASSBio-579 [591774-47-9]
  13. LASSBio-581 [591774-48-0]
  14. LASSBio-632
  15. LASSBio-680
  16. LASSBio-724
  17. LASSBio-729 [66307-58-2]
  18. LASSBio-730
  19. McN 261 [1044-59-3]
  20. Nefazodone
  21. Niaprazine
  22. Oxypertine
  23. PD-158771 [189152-50-9]
  24. PO-219
  25. Trazodone
  26. WIN 18,437 [4121-77-1]

See also

References

  1. ^ World Health Organization (WHO) (2006). "The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances" (PDF). Archived from the original (PDF) on 2008-12-14. Retrieved 27 April 2010.
  2. ^ "1-Phenylpiperazine".

External links


Piperazines
Categories