Protein-coding gene in the species Homo sapiens
Regulator of G-protein signaling 5 is a protein that in humans is encoded by the RGS5 gene.[5][6]
The regulator of G protein signaling (RGS) proteins are signal transduction molecules that have structural homology to SST2 of Saccharomyces cerevisiae and EGL-10 of Caenorhabditis elegans. Multiple genes homologous to SST2 are present in higher eukaryotes. RGS proteins are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators.[6]
Interactions
RGS5 has been shown to interact with GNAO1,[7][8] GNAI2[7][8] and GNAI3.[7][8]