Rajesh Thakker
Professor Rajesh Thakker in 2014, portrait via the Royal Society
Born
Rajesh Vasantlal Thakker

(1954-08-27) 27 August 1954 (age 69)[3]
Alma materUniversity of Cambridge (MA, MB BChir, MD, ScD)
SpouseJulie Clare Magee[3]
Awards
Scientific career
Fields
Institutions
Doctoral students
  • Michael Bowl[4]
  • Karin Bradley[5]
  • Katherine Gaynor[6]
  • Poloko Leotlela[7]
  • Manuel Lemos[8]
  • Mahsa Javid[9]
  • Jeshmi Jeyabalan[10]
  • Jeremy Turner[11]
  • Fiona Wu[12]
Websitewww.ocdem.ox.ac.uk/rajesh-thakker

Rajesh Vasantlal Thakker (born 1954) FRS FMedSci FRCPath FRCPE FRCP is May Professor of Medicine in the Nuffield Department of Clinical Medicine at the University of Oxford and a Fellow of Somerville College, Oxford.[13] Thakker is also a Consultant physician at the Churchill Hospital and the John Radcliffe Hospital, Chairman of the Efficacy and Mechanism Evaluation (EME) Board and Principal Investigator (PI) at the Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM).[14][15][16][17][18][19][20][21]

Education

Thakker was educated at Pembroke College, Cambridge where he was awarded his Master of Arts (MA), Bachelor of Medicine (MB BChir), Doctor of Medicine (MD) and Doctor of Science (ScD) degrees. He completed his clinical training at Middlesex Hospital Medical School.[3]

Research

Thakker's research investigates neuroendocrine tumours such as multiple endocrine neoplasia type 1 (MEN1)[2][20][22][23] and the molecular basis of disorders of calcium homeostasis.[15][16] He has supervised nine successful Doctor of Philosophy students[4][5][6][7][8][9][10][11][12] and his research has been funded by the Medical Research Council (MRC).[24]

Thakker has edited several books including Genetic and Molecular Biological Aspects of Endocrine Disease,[25] Molecular Genetics of Endocrine Disorders,[26] and Genetics of Bone Biology and Skeletal Disease.[27]

Awards and honours

Thakker was elected a Fellow of the Royal Society in 2014. His nomination reads:

Thakker has made a sustained series of major contributions to endocrinology, particularly parathyroid and renal disorders affecting calcium homeostasis. His research at the basic-science and clinical interface has resulted in seminal gene discoveries and insights into molecular, cellular and physiological mechanisms. These include: identification of functional pathways of calcium-sensing, through characterisation of mutations of the calcium-sensing-receptor, a G-protein-coupled- receptor (GPCR), and its signalling pathway through G-protein-alpha-11-subunit (Gα11) and adaptor-protein-2-sigma-subunit (AP2σ), which regulates GPCR endocytosis; and defining a molecular-based taxonomy of syndromic and non-syndromic hyperparathyroid and hypoparathyroid disorders that has resulted in new pathophysiological insights and advances in diagnosis and treatment.[1]

Personal life

Thakker is married to Julie Clare Magee and has one daughter.[3] He is a school governor at Oxford High School, Oxford.[28]

References

  1. ^ a b "Professor Rajesh Thakker FMedSci FRS". London: The Royal Society. Archived from the original on 2014-08-11.
  2. ^ a b c Professor Rajesh Thakker FRS FMedSci, The Academy of Medical Sciences
  3. ^ a b c d e THAKKER. "THAKKER, Prof. Rajesh Vasantlal". Who's Who. Vol. 2014 (online edition via Oxford University Press ed.). A & C Black. ((cite encyclopedia)): Unknown parameter |othernames= ignored (help) (Subscription or UK public library membership required.) (subscription required)
  4. ^ a b Bowl, Michael Richard (2003). Molecular genetics of hypoparathyroid disorders (DPhil thesis). University of Oxford.
  5. ^ a b Bradley, Karin J. (2006). Molecular genetics of the hyperparathyroidism-jaw tumour syndrome (DPhil thesis). University of Oxford.
  6. ^ a b Gaynor, Katherine Ursula (2011). The role of the transcription factor GATA3 in calcium homeostasis and tumourigenesis (DPhil thesis). University of Oxford.
  7. ^ a b Leotlela, Poloko D. (2003). Molecular genetics of multiple endocrine neoplasia type 1 and related disorders (DPhil thesis). University of Oxford.
  8. ^ a b Loureiro de Lemos, Manuel C. (2007). Genetic and phenotypic studies of the multiple endocrine neoplasia type 1 syndrome (DPhil thesis). University of Oxford.
  9. ^ a b Javid, Mahsa (2012). Gene modifiers and novel therapies for multiple endocrine neoplasia type 1 (DPhil thesis). University of Oxford.
  10. ^ a b Jeyabalan, Jeshmi (2008). Role of sedlin in spondyloepiphyseal dysplasia tarda (DPhil thesis). University of Oxford.
  11. ^ a b Turner, Jeremy James Osborne (2003). Molecular genetics of renal tubular disorders affecting urate transport (DPhil thesis). University of Oxford.
  12. ^ a b Wu, Fiona (2014). Dent's disease and the chloride channel, CLC-5 (DPhil thesis). University of Oxford.
  13. ^ Professor Rajesh Thakker, Somerville College, University of Oxford
  14. ^ Prof Rajesh V Thakker, Oxford Centre for Diabetes, Endocrinology and Metabolism OCDEM
  15. ^ a b Rajesh Thakker publications indexed by Microsoft Academic
  16. ^ a b Rajesh Thakker's publications indexed by the Scopus bibliographic database. (subscription required)
  17. ^ Attention: This template (((cite pmid))) is deprecated. To cite the publication identified by PMID 24622412, please use ((cite journal)) with |pmid=24622412 instead.
  18. ^ Attention: This template (((cite pmid))) is deprecated. To cite the publication identified by PMID 8559248, please use ((cite journal)) with |pmid=8559248 instead.
  19. ^ Attention: This template (((cite pmid))) is deprecated. To cite the publication identified by PMID 18177818, please use ((cite journal)) with |pmid=18177818 instead.
  20. ^ a b Attention: This template (((cite pmid))) is deprecated. To cite the publication identified by PMID 8813042, please use ((cite journal)) with |pmid=8813042 instead.
  21. ^ Attention: This template (((cite pmid))) is deprecated. To cite the publication identified by PMID 12434154, please use ((cite journal)) with |pmid=12434154 instead.
  22. ^ Attention: This template (((cite pmid))) is deprecated. To cite the publication identified by PMID 11739416, please use ((cite journal)) with |pmid=11739416 instead.
  23. ^ Attention: This template (((cite pmid))) is deprecated. To cite the publication identified by PMID 9215690, please use ((cite journal)) with |pmid=9215690 instead.
  24. ^ UK Government research grants awarded to Rajesh Thakker, via Research Councils UK
  25. ^ Template:Cite isbn
  26. ^ Template:Cite isbn
  27. ^ Template:Cite isbn
  28. ^ "Oxford High School GDST School Governors". Archived from the original on 2014-08-11.

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