Siv G. E. Andersson
Born
Siv Gun Elisabeth Andersson

1959 (age 64–65)
EducationPh.D.
Alma materUppsala University
Scientific career
FieldsEvolutionary biology
InstitutionsUppsala University, University of Cambridge
Doctoral advisorCharles Kurland
Websitewww.icm.uu.se/molecular-evolution/andersson-siv/

Siv Gun Elisabeth Andersson (born 1959) is a Swedish evolutionary biologist, professor of molecular evolution at Uppsala University.[1] She is member of both the Royal Swedish Academy of Sciences and of Engineering.[2][3] She is also Head of basic research at the Knut and Alice Wallenberg Foundation[4] and has been co-director of the Swedish national center for large-scale research Science for Life Laboratory between 2017 and 2021.[5] Her research focuses on the evolution of bacteria, mainly on intracellular parasites.

Education and career

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Andersson grew up in Horndal, Dalarna. Her mother was home care assistant and her father was employed in the wood industry.[6] She studied Biology at Uppsala University, since the programme was the only one that had a course about DNA. She defended her PhD in molecular biology in 1990, under the supervision of Charles Kurland.[7] She applied for a postdoctoral stipend from EMBO to continue her research in the United States, but ended up obtaining a research position at the MRC Laboratory of Molecular Biology in Cambridge.[6] She became professor of molecular evolution in 2000, at the Uppsala University's Evolutionary Biology Center.[6] She was elected at the Royal Swedish Academy of Sciences in 2005.[2]

Andersson has been very active in developing the Swedish national center for large-scale research Science for Life Laboratory, especially its DNA sequencing and bioinformatics platforms. She served as Co-director for the center between 2017 and 2021.[5]

During the 2020 COVID-19 pandemic, she contributed, together with Lars Engstrand and with the financial support of the Knut and Alice Wallenberg Foundation, to establish the first large-scale testing facility in Sweden[8][9]

Research

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Andersson's research first focused around the role of codon usage in shaping bacterial genomes.[10] After her postdoctoral fellowship, she contributed to sequence one of the first genome of an obligate intracellular parasite, Rickettsia prowazekii, the causative agent of epidemic typhus.[11]

In her later career, her research continued to explore bacteria and their relationships with their different hosts.[12] In particular, she is interested in the genomic consequences of long-term associations of intracellular bacteria.[13] She explored the evolution of Bartonella,[14] Wolbachia,[15] and Planctomycetota,[16] among others.

Andersson has published over 200 peer-reviewed articles, and has an h-index of 61, as of 2022.[17]

Notable awards and honors

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References

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  1. ^ ""Researcher Profile: Siv Andersson"". Retrieved 2022-03-08.
  2. ^ a b ""KVA Medlemssida Siv Andersson"" (in Swedish). Retrieved 2022-03-09.
  3. ^ a b ""IVA Medlemssida Andersson, Siv"" (in Swedish). Retrieved 2022-03-09.
  4. ^ ""New Program on Data-Driven Life Science"". 26 October 2020. Retrieved 2022-03-08.
  5. ^ a b ""Siv Andersson new Co-Director for SciLifeLab"". 18 May 2017. Retrieved 2022-03-08.
  6. ^ a b c ""Tidningen Curie: Hon blev DNA-forskare för att förstå livet"" (in Swedish). 28 February 2017. Retrieved 2022-03-09.
  7. ^ Andersson, Siv Gun Elisabeth. (1990). Translation, antibiotics and codon evolution. Uppsala University. ISBN 91-554-2551-8. OCLC 22568986. Retrieved 2021-01-16.
  8. ^ ""Siv Andersson: Från nyfikenhet till nytta under pandemin"" (in Swedish). Retrieved 2022-03-09.
  9. ^ Törnwall, Mikael (20 May 2020). ""Wallenbergs coronakupp: byggde ett labb utan lov"". Svenska Dagbladet (in Swedish). Retrieved 2022-03-09.
  10. ^ Andersson, SG; Kurland, CG (June 1990). "Codon preferences in free-living microorganisms". Microbiological Reviews. 54 (2): 198–210. doi:10.1128/mr.54.2.198-210.1990. PMC 372768. PMID 2194095.
  11. ^ Andersson, SG; Zomorodipour, A; Andersson, JO; Sicheritz-Pontén, T; Alsmark, UC; Podowski, RM; Näslund, AK; Eriksson, AS; Winkler, HH; Kurland, CG (12 November 1998). "The genome sequence of Rickettsia prowazekii and the origin of mitochondria". Nature. 396 (6707): 133–40. Bibcode:1998Natur.396..133A. doi:10.1038/24094. PMID 9823893. S2CID 4379381.
  12. ^ Toft, C; Andersson, SG (July 2010). "Evolutionary microbial genomics: insights into bacterial host adaptation". Nature Reviews. Genetics. 11 (7): 465–75. doi:10.1038/nrg2798. PMID 20517341. S2CID 40576224.
  13. ^ Sällström, B; Andersson, SG (October 2005). "Genome reduction in the alpha-Proteobacteria". Current Opinion in Microbiology. 8 (5): 579–85. doi:10.1016/j.mib.2005.08.002. PMID 16099701.
  14. ^ Guy, L; Nystedt, B; Toft, C; Zaremba-Niedzwiedzka, K; Berglund, EC; Granberg, F; Näslund, K; Eriksson, AS; Andersson, SG (March 2013). "A gene transfer agent and a dynamic repertoire of secretion systems hold the keys to the explosive radiation of the emerging pathogen Bartonella". PLOS Genetics. 9 (3): e1003393. doi:10.1371/journal.pgen.1003393. PMC 3610622. PMID 23555299.
  15. ^ Klasson, L; Westberg, J; Sapountzis, P; Näslund, K; Lutnaes, Y; Darby, AC; Veneti, Z; Chen, L; Braig, HR; Garrett, R; Bourtzis, K; Andersson, SG (7 April 2009). "The mosaic genome structure of the Wolbachia wRi strain infecting Drosophila simulans". Proceedings of the National Academy of Sciences of the United States of America. 106 (14): 5725–30. Bibcode:2009PNAS..106.5725K. doi:10.1073/pnas.0810753106. PMC 2659715. PMID 19307581.
  16. ^ Mahajan, M; Yee, B; Hägglund, E; Guy, L; Fuerst, JA; Andersson, SGE (1 April 2020). "Paralogization and New Protein Architectures in Planctomycetes Bacteria with Complex Cell Structures". Molecular Biology and Evolution. 37 (4): 1020–1040. doi:10.1093/molbev/msz287. PMID 31808939.
  17. ^ "Google Scholar: Siv Andersson". scholar.google.com. Retrieved 9 March 2022.
  18. ^ ""Letterstedska prisen 2002"" (in Swedish). KVA. 4 March 2002. Retrieved 2021-01-14.
  19. ^ "People in the EMBO Communities". people.embo.org. Retrieved 9 March 2022.
  20. ^ ""Kungl. Vetenskapsakademien: Nya ledamöter invalda, pressmeddelande 2005-02-10" (in Swedish). Retrieved 2022-03-09.
  21. ^ ""Laureates"" (in Swedish). KVA. Retrieved 2021-01-17.
  22. ^ "Miljonanslag för stark forskningsmiljö till Uppsala" (in Swedish). 2005-02-17. Retrieved 2021-01-14.
  23. ^ "ESEB Officers - ESEB | European Society for Evolutionary Biology". eseb.org.
  24. ^ "Bee bacteria working as vitamin factories | Knut and Alice Wallenberg Foundation". kaw.wallenberg.org. Retrieved 9 March 2022.
  25. ^ ""75 million in Wallenberg grant extension to Gunnar von Heijne - Department of Biochemistry and Biophysics"". www.dbb.su.se. Retrieved 2021-01-14.
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