Speio and her other sisters appear to Thetis when she cries out in sympathy for the grief of Achilles at the slaying of his friend Patroclus.[5]
In some accounts, Spio, together with her sisters Cymodoce, Nesaea and Thalia, was one of the nymphs in the train of Cyrene.[6] Later on, these four together with their other sisters Thetis, Melite and Panopea, were able to help the hero Aeneas and his crew during a storm.[7]
^Virgil, Georgics 4.338 "But his mother heard the cry from her bower beneath the river's depths. About her the Nymphs were spinning fleeces of Miletus, dyed with rich glassy hue – Drymo and Xantho, Ligea and Phyllodoce, their shining tresses floating over snowy necks; Nesaea and Spio, Thalia and Cymodoce [four Nereids];"