Tumors

Conditions

Benign tumors	Hyperplasia Cyst Pseudocyst Hamartoma
Malignant progression	Dysplasia Carcinoma in situ Cancer Metastasis Primary tumor Sentinel lymph node
Topography	Head and neck (oral, nasopharyngeal) Digestive system Respiratory system Bone Skin Blood Urogenital Nervous system Endocrine system
Histology	Carcinoma Sarcoma Blastoma Papilloma Adenoma
Other	Precancerous condition Paraneoplastic syndrome

Staging/grading

Carcinogenesis

Misc.

Oral, Digestive, Respiratory

Tumors of lip, oral cavity and pharynx / head and neck cancer

Oral cancer

Salivary gland

malignant epithelial tumors	Acinic cell carcinoma Mucoepidermoid carcinoma Adenoid cystic carcinoma Salivary duct carcinoma Epithelial-myoepithelial carcinoma Polymorphous low-grade adenocarcinoma Hyalinizing clear cell carcinoma
benign epithelial tumors	Pleomorphic adenoma Warthin's tumor
ungrouped	Oncocytoma

Tongue

Oropharynx

Digestive system neoplasia

GI tract

Upper

Esophagus	Squamous cell carcinoma Adenocarcinoma
Stomach	Gastric carcinoma Signet ring cell carcinoma Gastric lymphoma MALT lymphoma Linitis plastica Hereditary diffuse gastric cancer

Lower

Small intestine	Duodenal cancer Adenocarcinoma
Appendix	Carcinoid Pseudomyxoma peritonei
Colon/rectum	Colorectal polyp: adenoma, hyperplastic, juvenile, sessile serrated adenoma, traditional serrated adenoma, Peutz–Jeghers, Cronkhite–Canada Polyposis syndromes: Juvenile MUTYH-associated Familial adenomatous/Gardner's Polymerase proofreading-associated Serrated polyposis Neoplasm: Adenocarcinoma Familial adenomatous polyposis Hereditary nonpolyposis colorectal cancer
Anus	Squamous cell carcinoma

Upper and/or lower

Accessory

Liver	malignant: Hepatocellular carcinoma Fibrolamellar Hepatoblastoma Liver angiosarcoma benign: Hepatocellular adenoma Cavernous hemangioma hyperplasia: Focal nodular hyperplasia Nodular regenerative hyperplasia
Biliary tract	bile duct: Cholangiocarcinoma Klatskin tumor gallbladder: Gallbladder cancer
Pancreas	exocrine pancreas: Adenocarcinoma Pancreatic ductal carcinoma cystic neoplasms: Serous microcystic adenoma Intraductal papillary mucinous neoplasm Mucinous cystic neoplasm Solid pseudopapillary neoplasm Pancreatoblastoma

Peritoneum

Cancer involving the respiratory tract

Upper RT

Nasal cavity: Esthesioneuroblastoma

Nasopharynx: Nasopharyngeal carcinoma; Nasopharyngeal angiofibroma

Larynx: Laryngeal cancer; Laryngeal papillomatosis

Lower RT

Trachea

Tracheal tumor

Lung

Non-small-cell lung carcinoma	Squamous-cell carcinoma Adenocarcinoma (Mucinous cystadenocarcinoma) Large-cell lung carcinoma Rhabdoid carcinoma Sarcomatoid carcinoma Carcinoid Salivary gland–like carcinoma Adenosquamous carcinoma Papillary adenocarcinoma Giant-cell carcinoma
Small-cell carcinoma	Combined small-cell carcinoma
Non-carcinoma	Sarcoma Lymphoma Immature teratoma Melanoma
By location	Pancoast tumor Solitary pulmonary nodule Central lung Peripheral lung Bronchial leiomyoma

Pleura

Mediastinum

Mediastinal tumors

Circulatory

v t e Lymphatic disease: organ and vessel diseases
Thymus	Abscess Hyperplasia Hypoplasia DiGeorge syndrome Ectopic thymus Thymoma Thymic carcinoma
Spleen	Asplenia Asplenia with cardiovascular anomalies Accessory spleen Polysplenia Wandering spleen Splenomegaly Banti's syndrome Splenic infarction Splenic tumor
Lymph node	Lymphadenopathy Generalized lymphadenopathy Castleman's disease Intranodal palisaded myofibroblastoma Kikuchi disease Tonsils see Template:Respiratory pathology
Lymphatic vessels	Lymphangitis Lymphangiectasia Lymphedema Primary lymphedema Congenital lymphedema Lymphedema praecox Lymphedema tarda Lymphedema–distichiasis syndrome Milroy's disease Secondary lymphedema Bullous lymphedema Factitial lymphedema Postinflammatory lymphedema Postmastectomy lymphangiosarcoma Waldmann disease

v t e Tumours of blood vessels
Blood vessel	Hemangiosarcoma Blue rubber bleb nevus syndrome Hemangioendothelioma Composite Endovascular papillary Epithelioid Kaposiform Infantile Retiform) Spindle cell Proliferating angioendotheliomatosis Hemangiopericytoma Infantile hemangiopericytoma Venous lake Kaposi's sarcoma African cutaneous African lymphadenopathic AIDS-associated Classic Immunosuppression-associated Hemangioblastoma Hemangioma Capillary Cavernous Glomeruloid Microvenular Targeted hemosiderotic Angioma Cherry Seriginosum Spider Tufted Universal angiomatosis Angiokeratoma of Mibelli Angiolipoma Pyogenic granuloma Intravascular papillary endothelial hyperplasia
Lymphatic	Lymphangioma/lymphangiosarcoma Lymphangioma circumscriptum Acquired progressive lymphangioma PEComa Lymphangioleiomyomatosis Cystic hygroma Multifocal lymphangioendotheliomatosis Lymphangiomatosis
Either	Angioma/angiosarcoma Angiofibroma

Soft tissues

Tumours of bone and cartilage

Diaphysis

Metaphysis

Osteoblast	Osteoid osteoma Osteoblastoma Osteoma/osteosarcoma
Chondroblast	Chondroma/ecchondroma/enchondroma Enchondromatosis Extraskeletal chondroma Chondrosarcoma Mesenchymal chondrosarcoma Myxoid chondrosarcoma Osteochondroma Osteochondromatosis Chondromyxoid fibroma
Fibrous	Ossifying fibroma Fibrosarcoma

Epiphysis

Chondroblast	Chondroblastoma
Myeloid	Giant-cell tumor of bone

Other

Notochord	Chordoma

Skin cancer of nevi and melanomas

Melanoma

Nevus/
melanocytic nevus

Connective/soft tissue tumors and sarcomas

Not otherwise specified

Connective tissue neoplasm

Fibromatous

Fibroma/fibrosarcoma	Dermatofibrosarcoma protuberans Desmoplastic fibroma
Fibroma/fibromatosis	Aggressive fibromatosis Aggressive infantile fibromatosis Aponeurotic fibroma Collagenous fibroma Diffuse infantile fibromatosis Familial myxovascular fibromas Fibroma of tendon sheath Fibromatosis colli Infantile digital fibromatosis Juvenile hyaline fibromatosis Plantar fibromatosis Pleomorphic fibroma Oral submucous fibrosis Pachydermodactyly
Histiocytoma/histiocytic sarcoma	Benign fibrous histiocytoma Malignant fibrous histiocytoma Atypical fibroxanthoma Solitary fibrous tumor

Synovial-like

General	Myoma/myosarcoma
Smooth muscle	Leiomyoma/leiomyosarcoma
Skeletal muscle	Rhabdomyoma/rhabdomyosarcoma: Embryonal rhabdomyosarcoma Sarcoma botryoides Alveolar rhabdomyosarcoma
Leiomyoma Angioleiomyoma Angiolipoleiomyoma Genital leiomyoma Leiomyosarcoma Multiple cutaneous and uterine leiomyomatosis syndrome Multiple cutaneous leiomyoma Neural fibrolipoma Solitary cutaneous leiomyoma STUMP

Complex mixed and stromal

Mesothelial

Genital and urogenic

Breast cancer

General

Treatment

Types

Ductal	Ductal carcinoma in situ (DCIS) Paget's disease of the breast Comedocarcinoma Invasive ductal carcinoma (IDC) Intraductal papilloma
Lobular	Lobular carcinoma in situ (LCIS) Invasive lobular carcinoma (ILC) Hereditary lobular breast cancer
Fibroepithelials/stromal	Fibroadenoma Phyllodes tumor
Other	Medullary breast carcinoma Metaplastic breast cancer (MBC) Male breast cancer Inflammatory breast cancer Precursor lesions Atypical ductal hyperplasia Nipple adenoma

Other

Tumors of the female urogenital system

Adnexa

Ovaries

Glandular and epithelial/
surface epithelial-
stromal tumor

CMS:	Ovarian serous cystadenoma Mucinous cystadenoma Cystadenocarcinoma Papillary serous cystadenocarcinoma Krukenberg tumor
Endometrioid tumor Ovarian clear-cell carcinoma Brenner tumour

Sex cord–gonadal stromal

Germ cell

Fibroma

Meigs' syndrome

Fallopian tube

Adenomatoid tumor

Uterus

Myometrium	Uterine fibroids/leiomyoma Leiomyosarcoma Adenomyoma
Endometrium	Endometrioid tumor Uterine papillary serous carcinoma Endometrial intraepithelial neoplasia Uterine clear-cell carcinoma
Cervix	Cervical intraepithelial neoplasia Clear-cell carcinoma SCC Glassy-cell carcinoma Villoglandular adenocarcinoma
Placenta	Choriocarcinoma Gestational trophoblastic disease
General	Uterine sarcoma Mixed Müllerian tumor

Vagina

Vulva

Tumors of the male urogenital system

Testicles

Sex cord–
gonadal stromal

Sertoli–Leydig cell tumour
- Sertoli cell tumour
- Leydig cell tumour

Germ cell

G	Seminoma Spermatocytic tumor Germ cell neoplasia in situ
NG	Embryonal carcinoma Endodermal sinus tumor Gonadoblastoma Teratoma Choriocarcinoma Embryoma

Prostate

Penis

Tumors of the urinary and genital systems

Kidney

Glandular and epithelial neoplasm	Renal cell carcinoma Renal oncocytoma
Mixed tumor	Wilms' tumor Mesoblastic nephroma Clear-cell sarcoma of the kidney Angiomyolipoma Cystic nephroma Metanephric adenoma
by location	Renal medullary carcinoma Juxtaglomerular cell tumor Renal medullary fibroma

Ureter

Ureteral neoplasm

Bladder

Urethra

Other

Malignant fibrous histiocytoma

Sensory and Nervous, Endocrine

v t e Eye neoplasm
Melanoma	Uveal melanoma Ciliary body melanoma
Other	Choroidal nevus Medulloepithelioma/Diktyoma Intraocular lymphoma Orbital lymphoma Optic nerve sheath meningioma Optic nerve tumor Retinoblastoma Schwannoma Visual pathway glioma

Tumours of the nervous system

Endocrine

Sellar:	Craniopharyngioma Pituicytoma
Other:	Pinealoma

CNS

Neuroepithelial
(brain tumors,
spinal tumors)

Glioma

Astrocyte	Astrocytoma Pilocytic astrocytoma Pleomorphic xanthoastrocytoma Subependymal giant cell astrocytoma Fibrillary astrocytoma Anaplastic astrocytoma Glioblastoma
Oligodendrocyte	Oligodendroglioma Anaplastic oligodendroglioma
Ependyma	Ependymoma Subependymoma
Choroid plexus	Choroid plexus tumor Choroid plexus papilloma Choroid plexus carcinoma
Multiple/unknown	Oligoastrocytoma Gliomatosis cerebri Gliosarcoma

Mature
neuron

CNS embryonal tumors

Meninges

Hematopoietic

Primary central nervous system lymphoma

PNS:

Neuroblastoma
- Esthesioneuroblastoma
- Ganglioneuroblastoma
Nerve sheath tumor
Cranial and paraspinal nerves
- Neurofibroma
- Neurofibromatosis
Neurilemmoma/Schwannoma
- Acoustic neuroma
Malignant peripheral nerve sheath tumor

Other

WHO classification of the tumors of the central nervous system

Note: Not all brain tumors are of nervous tissue, and not all nervous tissue tumors are in the brain (see brain metastasis).

v t e Tumours of endocrine glands
Pancreas	Pancreatic cancer Pancreatic neuroendocrine tumor α: Glucagonoma β: Insulinoma δ: Somatostatinoma G: Gastrinoma VIPoma
Pituitary	Pituitary adenoma: Prolactinoma ACTH-secreting pituitary adenoma GH-secreting pituitary adenoma Craniopharyngioma Pituicytoma
Thyroid	Thyroid cancer (malignant): epithelial-cell carcinoma Papillary Follicular/Hurthle cell Parafollicular cell Medullary Anaplastic Lymphoma Squamous-cell carcinoma Benign Thyroid adenoma Struma ovarii
Adrenal tumor	Cortex Adrenocortical adenoma Adrenocortical carcinoma Medulla Pheochromocytoma Neuroblastoma Paraganglioma
Parathyroid	Parathyroid neoplasm Adenoma Carcinoma
Pineal gland	Pinealoma Pinealoblastoma Pineocytoma
MEN	1 2A 2B

Lymphoid, Myeloid

Leukaemias, lymphomas and related disease

B cell
(lymphoma,
leukemia)
(most CD19

CD20)

By
development/
marker

TdT+	ALL (Precursor B acute lymphoblastic leukemia/lymphoma)
CD5+	naive B cell (CLL/SLL) mantle zone (Mantle cell)
CD22+	Prolymphocytic CD11c+ (Hairy cell leukemia)
CD79a+	germinal center/follicular B cell (Follicular Burkitt's GCB DLBCL Primary cutaneous follicle center lymphoma) marginal zone/marginal zone B-cell (Splenic marginal zone MALT Nodal marginal zone Primary cutaneous marginal zone lymphoma)
RS (CD15+, CD30+)	Classic Hodgkin lymphoma (Nodular sclerosis) CD20+ (Nodular lymphocyte predominant Hodgkin lymphoma)
PCDs/PP (CD38+/CD138+)	see immunoproliferative immunoglobulin disorders

By infection

Cutaneous

T/NK

T cell
(lymphoma,
leukemia)
(most CD3

CD4
CD8)

By
development/
marker

TdT+: ALL (Precursor T acute lymphoblastic leukemia/lymphoma)

prolymphocyte (Prolymphocytic)

Cutaneous

MF+variants	indolent: Mycosis fungoides Pagetoid reticulosis Granulomatous slack skin aggressive: Sézary disease Adult T-cell leukemia/lymphoma
Non-MF	CD30-: Non-mycosis fungoides CD30− cutaneous large T-cell lymphoma Pleomorphic T-cell lymphoma Lymphomatoid papulosis type B CD30+: CD30+ cutaneous T-cell lymphoma Secondary cutaneous CD30+ large-cell lymphoma Lymphomatoid papulosis type A

Other
peripheral

By infection

HTLV-1 (Adult T-cell leukemia/lymphoma)

NK cell/
(most CD56)

T or NK

Lymphoid+
myeloid

Acute biphenotypic leukaemia

Lymphocytosis

Cutaneous lymphoid hyperplasia

General

CFU-GM/
and other granulocytes

CFU-GM

Myelocyte

AML	Acute myeloblastic leukemia M0 M1 M2 APL/M3
MP	Chronic neutrophilic leukemia

Monocyte

AML	AMoL/M5 Myeloid dendritic cell leukemia
CML	Philadelphia chromosome Accelerated phase chronic myelogenous leukemia

Myelomonocyte

AML	M4
MD-MP	Juvenile myelomonocytic leukemia Chronic myelomonocytic leukemia

Other

Histiocytosis

CFU-Baso

AML	Acute basophilic

CFU-Eos

AML	Acute eosinophilic
MP	Chronic eosinophilic leukemia/Hypereosinophilic syndrome

MEP

CFU-Meg

MP	Essential thrombocythaemia Acute megakaryoblastic leukemia

CFU-E

AML	Erythroleukemia/M6
MP	Polycythaemia vera
MD	Refractory anemia Refractory anemia with excess of blasts Chromosome 5q deletion syndrome Sideroblastic anemia Paroxysmal nocturnal haemoglobinuria Refractory cytopenia with multilineage dysplasia

CFU-Mast

Mastocytoma	Mast cell leukemia Mast cell sarcoma Systemic mastocytosis
Mastocytosis	Diffuse cutaneous mastocytosis Erythrodermic mastocytosis Adult type of generalized eruption of cutaneous mastocytosis Urticaria pigmentosa Mast cell sarcoma Solitary mastocytoma
Systemic mastocytosis	Xanthelasmoidal mastocytosis

Multiple/unknown

AML	Acute panmyelosis with myelofibrosis Myeloid sarcoma
MP	Primary myelofibrosis Biphenotypic acute leukaemia

More

v t e Cancers from and involving the heart
Primary	Papillary fibroelastoma Rhabdomyoma Angiosarcoma Teratoma Cystic tumour of the atrioventricular nodal region
Other	Myxoma Atrial Lipoma Secondary