1 May – Peruvian–Bolivian War: Peruvian forces under Agustín Gamarra cross the Desaguadero River into Bolivia, seeking to expel Gran Colombian influence in the country.
July
6 July – Peruvian–Bolivian War: The Treaty of Piquiza is signed between Sucre and Gamarra. Gran Colombian troops are required to withdraw while Peruvian troops will remain for some time.
August
2 August – President Sucre presents his definitive resignation to Congress. Simultaneously, a new cabinet is appointed by decree, presided by José Miguel de Velasco.[3][4][5]
12 August – Andrés de Santa Cruz and José Miguel de Velasco are elected provisional president and vice president by the General Constituent Congress. Velasco assumes command pending the arrival of Santa Cruz.[6][7]