The 1942 United States Senate election in Nebraska was held on November 3, 1942.
Incumbent Independent George W. Norris lost re-election to a sixth term to Republican Kenneth Wherry.
Norris, a former Republican, was quoted as remarking, “I would rather go down to my political grave with a clear conscience than ride in the chariot of victory.” In part for his honesty with constituents even if it meant defeat, Norris was later featured in John F. Kennedy's Pulitzer Prize-winning Profiles in Courage.
|Democratic||John C. Mullen||5,211||5.84%|
|Democratic||George W. Olsen||1,105||1.24%|
|Democratic||Lawrence W. Moore||784||0.88%|
|Independent||George W. Norris||108,899||28.64%|
|Independent||Albert F. Ruthven||1,348||0.36%|