The 1949 All-Southwest Conference football team consists of American football players chosen by various organizations for All-Southwest Conference teams for the 1949 college football season. The selectors for the 1949 season included the Associated Press (AP) and the United Press (UP). Players selected as first-team players by both the AP and UP are designated in bold.

All Southwest selections

Backs

• Doak Walker, SMU (AP-1, UP-1)
• Adrian Burk, Baylor (AP-1, UP-1)
• Kyle Rote, SMU (AP-1, UP-1)
• Lindy Berry, TCU (AP-1, UP-1)
• Bob Smith, Texas A&M (AP-2, UP-2)
• Paul Campbell, Texas (UP-2)
• Gordon Wyatt, Rice (UP-2)
• Geno Mazzanti, Arkansas (UP-2)
• Randall Clay, Texas (AP-2)
• Bobby Lantrip, Rice (AP-2)
• Leon Campbell, Arkansas (AP-2)

Ends

• James "Froggy" Williams, Rice (AP-1, UP-1)
• J. D. Ison, Baylor (AP-1, UP-1)
• Ben Proctor, Texas (AP-2, UP-2)
• Jack Wolcott, Rice (AP-2)
• Frank Fischel, Arkansas (UP-2)

Tackles

• Ralph Murphy, Rice (AP-1, UP-1)
• Harold Kilman, TCU (AP-1, UP-2)
• Bobby Collier, SMU (AP-2)
• John Lunney, Arkansas (AP-2, UP-2)

Guards

• Don Mouser, Baylor (AP-1, UP-1)
• Bud McFadin, Texas (AP-1, UP-1 [t])
• Dan Wolfe, Texas (UP-1)
• Carl Schwarz, Rice (AP-2)
• Jack Halliday, SMU (AP-2)
• Charles Stone, Baylor (UP-2)

Centers

• Joe Watson, Rice (AP-1, UP-1)
• Bones Weatherly, Rice (AP-2, UP-2 [g])
• Eugene Huebner, Baylor (UP-2)

Key