The 1950 Duquesne Dukes football team was an American football team that represented Duquesne University as an independent during the 1950 college football season. In its first and only season under acting head coach Doc Skender, Duquesne compiled a 2–6–1 record and was outscored by a total of 265 to 169.^[1]

In January 1951, Duquesne president, the Rev. Vernon F. Gallagher, announced that the school had decided to suspend its participation in intercollegiate football. As reasons for the suspension, the school cited the manpower shortage resulting from the Korean War and noted that the school had suffered "heavy financial losses" from football over the last four years.^[2] The school did not resume competition in the sport until 1969.

Schedule

Date	Time	Opponent	Site	Result	Attendance	Source
September 17		at Saint Vincent	Latrobe, PA	T 14–14	9,800	[3]
September 23		at Villanova	Villanova Stadium Villanova, PA	L 28–39
September 30		at Florida	Florida Field Gainesville, FL	L 14–28	18,500	[4]
October 7		Boston University	Pitt Stadium Pittsburgh, PA	L 7–21	10,000	[5]
October 21		St. Bonaventure	Forbes Field Pittsburgh, PA	W 25–12		[6]
October 28	9:00 p.m.	at Louisville	duPont Manual Stadium Louisville, KY	W 27–20	12,000	[7][8][9]
November 4		at No. 14 Clemson	Memorial Stadium Clemson, SC	L 20–53	17,000	[10]
November 12		at Detroit	University of Detroit Stadium Detroit, MI	L 14–47	7,129	[11][12]
November 17		at Chattanooga	Chamberlain Field Chattanooga, TN	L 20–32	8,500	[13]
Homecoming Rankings from AP Poll released prior to the game All times are in Eastern time