2000 Music City Bowl
1234 Total
Ole Miss 36722 38
West Virginia 728140 49
DateDecember 28, 2000
StadiumAdelphia Coliseum (LP Field)
LocationNashville, Tennessee
PayoutUS$750,000 per team [1]
United States TV coverage
AnnouncersMark Jones, Gino Toretta, and Rob Stone
Music City Bowl
 < 1999  2001

In the 2000 Music City Bowl, West Virginia defeated Ole Miss 49–38. This game was also West Virginia Mountaineers football coach Don Nehlen's final game.[2] Although West Virginia won the game, it was notable because of a second half comeback by freshman Eli Manning. Down 49–16 in the fourth quarter, Ole Miss coach David Cutcliffe inserted Manning.[3] Ole Miss scored 22 unanswered points in the fourth quarter.