The 2001 International League season took place from April to September 2001.
The Louisville Bats defeated the Scranton/Wilkes-Barre Red Barons to win the league championship, also known as the Governor's Cup Finals.
| International League - North Division | ||||
|---|---|---|---|---|
| Team | Win | Loss | % | GB |
| Buffalo Bisons | 91 | 51 | .643 | – |
| Scranton/Wilkes-Barre Red Barons | 78 | 65 | .545 | 13½ |
| Syracuse Chiefs | 71 | 73 | .493 | 21 |
| Ottawa Lynx | 68 | 76 | .472 | 24 |
| Pawtucket Red Sox | 60 | 82 | .423 | 31 |
| Rochester Red Wings | 60 | 84 | .417 | 32 |
| International League - South Division | ||||
|---|---|---|---|---|
| Team | Win | Loss | % | GB |
| Norfolk Tides | 85 | 57 | .599 | – |
| Durham Bulls | 74 | 70 | .514 | 12 |
| Richmond Braves | 68 | 76 | .472 | 18 |
| Charlotte Knights | 67 | 77 | .000 | 19 |
| International League - West Division | ||||
|---|---|---|---|---|
| Team | Win | Loss | % | GB |
| Louisville Bats | 84 | 60 | .583 | – |
| Columbus Clippers | 67 | 76 | .469 | 16½ |
| Indianapolis Indians | 66 | 78 | .458 | 18 |
| Toledo Mud Hens | 65 | 79 | .451 | 19 |
| Date | Team | Score |
|---|---|---|
| September 5 | Buffalo at Scranton/Wilkes-Barre | 7–3 |
| September 6 | Buffalo at Scranton/Wilkes-Barre | 3–2 |
| September 7 | Scranton/Wilkes-Barre at Buffalo | 9–1 |
| September 8 | Scranton/Wilkes-Barre at Buffalo | 4–3 |
| September 9 | Scranton/Wilkes-Barre at Buffalo | 6–2(19) |
| Date | Team | Score |
|---|---|---|
| September 5 | Louisville at Norfolk | 5–2 |
| September 6 | Louisville at Norfolk | 4–0 |
| September 7 | Norfolk at Louisville | 1–0 |
| September 8 | Norfolk at Louisville | 7–1 |
| September 9 | Norfolk at Louisville | 2–0 |
| Date | Team | Score |
|---|---|---|
| September 10 | Scranton/Wilkes-Barre at Louisville | 2–1 |
| September 11 | Canceled due to September 11 attacks | – |
| September 12 | Canceled due to September 11 attacks | – |
| Semifinals | Governor's Cup Finals | ||||||||
| N1 | Scranton/Wilkes-Barre Red Barons | 2 | |||||||
| WC | Scranton/Wilkes-Barre Red Barons | 3 | |||||||
| WC | Scranton/Wilkes-Barre Red Barons | 0 | |||||||
| W1 | Louisville RiverBats | 1 | |||||||
| S1 | Norfolk Tides | 2 | |||||||
| W1 | Louisville RiverBats | 3 | |||||||