Debuts
Domestic
- 13 October - Binnelanders (M-Net/kykNET) (2005-2009)
- Going Nowhere Slowly (SABC3)
International
- 8 January -
Foyle's War (M-Net) - 31 January -
Dave the Barbarian (e.tv) - 3 February - Rescue Me (M-Net)
- 5 February - Lost (M-Net)
- 6 February - Arrested Development (E.tv)
- 24 February - The 4400 (M-Net)
- 2 March - Joey (M-Net)
- 2 March - Two and a Half Men (M-Net)
- 28 March - 8 Simple Rules (SABC3)
- 7 April - Desperate Housewives (M-Net)
- 8 July - The Bachelorette (M-Net Series)
- 20 October - House (M-Net)
- 16 November - The Closer (M-Net)
- /
/ Jakers! The Adventures of Piggley Winks (M-Net) - Fifi and the Flowertots (M-Net)
- Top Gear (BBC Prime)
- Brandy and Mister Whiskers (E.tv)
- American Dragon (E.tv)
6teen (SABC2)- New Captain Scarlet (M-Net)
- Legend of the Dragon (M-Net)
- Little Red Tractor (M-Net)
Mew Mew Power (M-Net)- The X's (SABC2)
- Peppa Pig (SABC2)
/
Creepschool (M-Net)- / W.I.T.C.H. (M-Net)
- Transformers: Energon (SABC2)
- Boohbah (SABC2)
- The Catherine Tate Show (BBC Prime)
- Funky Valley (M-Net)
- The Island of Inis Cool (M-Net)