Winners
- Best Picture:
- Letters from Iwo Jima
- Runner-up: The Queen
- Best Director:
- Paul Greengrass – United 93
- Runner-up: Clint Eastwood – Flags of Our Fathers and Letters from Iwo Jima
- Best Actor (TIE):
- Best Actress:
- Helen Mirren – The Queen
- Runner-up: Penélope Cruz – Volver
- Best Supporting Actor:
- Michael Sheen – The Queen
- Runner-up: Sergi López – Pan's Labyrinth (El laberinto del fauno)
- Best Supporting Actress:
- Luminița Gheorghiu – The Death of Mr. Lazarescu (Moartea domnului Lăzărescu)
- Runner-up: Jennifer Hudson – Dreamgirls
- Best Screenplay:
- Peter Morgan – The Queen
- Runner-up: Michael Arndt – Little Miss Sunshine
- Best Cinematography:
- Emmanuel Lubezki – Children of Men
- Runner-up: Tom Stern – Flags of Our Fathers and Letters from Iwo Jima
- Best Production Design:
- Eugenio Caballero – Pan's Labyrinth (El laberinto del fauno)
- Runner-up: Jim Clay, Veronica Falzon, and Geoffrey Kirkland – Children of Men
- Best Music Score:
- Alexandre Desplat – The Painted Veil and The Queen
- Runner-up: Thomas Newman – The Good German and Little Children
- Best Foreign-Language Film:
- The Lives of Others (Das Leben der Anderen) • Germany
- Runner-up: Volver • Spain
- Best Documentary/Non-Fiction Film:
- An Inconvenient Truth
- Runner-up: Darwin's Nightmare
- Best Animation:
- Happy Feet
- Runner-up: Cars
- The Douglas Edwards Experimental/Independent Film/Video Award:
- New Generation Award:
- Michael Arndt (screenwriter), Jonathan Dayton and Valerie Faris (co-directors) – Little Miss Sunshine
- Career Achievement Award:
- Special Citation:
- Jean-Pierre Melville's 1969 film Army of Shadows upon the occasion of its long-overdue U.S. release.
- Jonas Mekas for his contributions to American film culture as a filmmaker, critic and co-founder of Anthology Film Archives.