The 2006 Western Carolina Catamounts team represented Western Carolina University as a member of the Southern Conference (SoCon) during the 2006 NCAA Division I FCS football season. Led by fifth-year head coach Kent Briggs, the Catamounts compiled an overall record of 2–9 with a mark of 0–7 in conference play, placing last out of eight teams in the SoCon. Western Carolina played their home games at Bob Waters Field at E. J. Whitmire Stadium in Cullowhee, North Carolina.

Schedule

Date	Time	Opponent	Site	Result	Attendance
August 31		Chowan*	Bob Waters Field at E. J. Whitmire Stadium Cullowhee, NC	W 42–0	3,014
September 16		Eastern Kentucky*	Bob Waters Field at E. J. Whitmire Stadium Cullowhee, NC	W 20–17	8,247
September 23		at No. 3 Furman	Paladin Stadium Greenville, SC	L 7–42	14,232
September 30	6:00 p.m.	No. 25 Georgia Southern	Bob Waters Field at E. J. Whitmire Stadium Cullowhee, NC	L 14–24	10,483
October 7		at Elon	Rhodes Stadium Elon, NC	L 19–37	4,374
October 14		Chattanooga	Bob Waters Field at E. J. Whitmire Stadium Cullowhee, NC	L 14–17 OT	8,540
October 21	2:00 p.m.	at The Citadel	Johnson Hagood Stadium Charleston, SC	L 27–30 OT	15,495
October 28		at Wofford	Gibbs Stadium Spartanburg, SC	L 7–35	7,072
November 4		at Liberty*	Williams Stadium Lynchburg, VA	L 0–21	8,286
November 11	4:00 p.m.	No. 1 Appalachian State	Bob Waters Field at E. J. Whitmire Stadium Cullowhee, NC (Battle for the Old Mountain Jug)	L 9–31	13,742
November 18		at No. 3 (FBS) Florida*	Ben Hill Griffin Stadium Gainesville, FL	L 0–62	90,233
*Non-conference game Homecoming Rankings from The Sports Network Poll released prior to the game All times are in Eastern time

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