The 2018 All-Big 12 Conference football team consists of American football players chosen as All-Big 12 Conference players for the 2018 Big 12 Conference football season. The conference recognizes two official All-Big 12 selectors: (1) the Big 12 conference coaches selected separate offensive and defensive units and named first- and second-team players (the "Coaches" team); and (2) a panel of sports writers and broadcasters covering the Big 12 also selected offensive and defensive units and named first- and second-team players (the "Media" team).

Offensive selections

Quarterbacks

• Kyler Murray, Oklahoma (Coaches-1; Media-1)
• Will Grier, West Virginia (Coaches-2; Media-2)

Running backs

• Alex Barnes, Kansas State (Coaches-2; Media-1)
• Justice Hill, Oklahoma State (Coaches-1; Media-2)
• David Montgomery, Iowa State (Coaches-2; Media-1)
• Pooka Williams Jr., Kansas (Coaches-1; Media-2)

Fullbacks

• Andrew Beck, Texas (Coaches-1)
• Carson Meier, Oklahoma (Coaches-2)

Centers

• Zach Shackelford, Texas (Coaches-2; Media-1)
• Creed Humphrey, Oklahoma (Media-2)

Guards

• Ben Powers, Oklahoma (Coaches-1; Media-1)
• Dru Samia, Oklahoma (Coaches-1; Media-1)
• Jack Anderson, Texas Tech (Coaches-2; Media-2)
• Josh Sills, West Virginia (Coaches-2; Media-2)

Tackles

• Yodny Cajuste, West Virginia (Coaches-1; Media-1)
• Dalton Risner, Kansas State (Coaches-1; Media-1)
• Bobby Evans, Oklahoma (Coaches-1; Media-2)
• Cody Ford, Oklahoma (Coaches-2; Media-2)
• Hakeem Adeniji, Kansas (Coaches-2)

Tight ends

• Grant Calcaterra, Oklahoma (Coaches-1; Media-1)
• Trevon Wesco, West Virginia (Coaches-1; Media-2)
• Charlie Kolar, Iowa State (Coaches-2)

Receivers

• Marquise Brown, Oklahoma (Coaches-1; Media-1)
• Tylan Wallace, Oklahoma State (Coaches-1; Media-1)
• David Sills, West Virginia (Coaches-1; Media-2)
• Antoine Wesley, Texas Tech (Coaches-2; Media-1)
• Hakeem Butler, Iowa State (Coaches-2; Media-2)
• Jalen Reagor, TCU (Coaches-2)

Defensive selections

Defensive linemen

• Ben Banogu, TCU (Coaches-1; Media-1)
• Charles Omenihu, Texas (Coaches-1; Media-1)
• Daniel Wise, Kansas (Coaches-1; Media-1)
• Jordan Brailford, Oklahoma State (Coaches-1; Media-2)
• L. J. Collier, TCU (Coaches-1; Media-2)
• James Lynch, Baylor (Coaches-2; Media-1)
• Kenny Bigelow Jr., West Virginia (Coaches-2; Media-2)
• Ray Lima, Iowa State (Coaches-2; Media-2)
• JaQuan Bailey, Iowa State (Coaches-2)
• Jarrell Owens, Oklahoma State (Coaches-2)

Linebackers

• Dakota Allen, Texas Tech (Coaches-1; Media-1)
• Joe Dineen Jr., Kansas (Coaches-1; Media-1)
• David Long Jr., West Virginia (Coaches-1; Media-1)
• Gary Johnson, Texas (Coaches-2; Media-2)
• Clay Johnston, Baylor (Coaches-2; Media-2)
• Kenneth Murray, Oklahoma (Coaches-2; Media-2)

Defensive backs

• Kris Boyd, Texas (Coaches-1; Media-1)
• Adrian Frye, Texas Tech (Coaches-1; Media-1)
• Kenny Robinson, West Virginia (Coaches-1; Media-1)
• Caden Sterns, Texas (Coaches-1; Media-1)
• Greg Eisworth, Iowa State (Coaches-1; Media-2)
• Jeff Gladney, TCU (Coaches-2; Media-2)
• Brian Peavy, Iowa State (Coaches-2; Media-2)
• Ridwan Issahaku, TCU (Coaches-2; Media-2)
• Duke Shelley, Kansas State (Coaches-2)
• A. J. Green, Oklahoma State (Coaches-2)

Special teams

Kickers

• Austin Seibert, Oklahoma (Coaches-1; Media-1)
• Clayton Hatfield, Texas Tech (Coaches-1; Media-2)
• Cameron Dicker, Texas (Coaches-2)

Punters

• Drew Galitz, Baylor (Coaches-1; Media-1)
• Kyle Thompson, Kansas (Coaches-2; Media-2)

All-purpose / Return specialists

• Pooka Williams, Jr., Kansas (Coaches-1; Media-1)
• Tre Brown, Oklahoma (Coaches-2)
• CeeDee Lamb, Oklahoma (Media-2)
• Kene Nwangwu, Iowa State (Coaches-2)

Key