5-EtO-DMT Structure.svg
  • 2-(5-Ethoxy-1H-indol-3-yl)-N,N-dimethylethanamine
CAS Number
PubChem CID
CompTox Dashboard (EPA)
Chemical and physical data
Molar mass232.327 g·mol−1
3D model (JSmol)
  • CCOc(cc12)ccc1[nH]cc2CCN(C)C
  • InChI=1S/C14H20N2O/c1-4-17-12-5-6-14-13(9-12)11(10-15-14)7-8-16(2)3/h5-6,9-10,15H,4,7-8H2,1-3H3 checkY
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5-Ethoxy-DMT (5-ethoxy-N,N-dimethyltryptamine, 5-EtO-DMT, O-ethylbufotenine) is a tryptamine derivative which has been previously synthesized as a chemical intermediate, but has not been studied to determine its pharmacology.[1][unreliable source?]

The widespread recreational use of N,N-dialkylated 5-methoxytryptamine derivatives including 5-MeO-DMT, 5-MeO-MiPT and 5-MeO-DiPT has led to concern that the 5-ethoxy homologs of these drugs could emerge as novel designer drugs, and consequently 5-EtO-DMT and other derivatives including 5-EtO-DET, 5-EtO-DPT, 5-EtO-DiPT, 5-EtO-DALT, 5-EtO-MPT, 5-EtO-MiPT, 5-EtO-EiPT, 5-EtO-MET and 5-EtO-EPT have been synthesized as analytical standards in order to facilitate future research into these compounds.[2]

See also


  1. ^ TIHKAL #19
  2. ^ Tearavarich R, Hahnvajanawong V, Dempster N, Daley PF, Cozzi NV, Brandt SD (September 2011). "Microwave-accelerated preparation and analytical characterization of 5-ethoxy-N,N-dialkyl-[α,α,β,β-H(4) ]- and [α,α,β,β-D(4) ]-tryptamines". Drug Testing and Analysis. 3 (9): 597–608. doi:10.1002/dta.223. PMID 21960544.