RPL29
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 4UG0, 4V6X, 5AJ0, 4UJD, 4D67, 4D5Y, 4UJE, 4UJC
Identifiers
Aliases	RPL29, HIP, HUML29, RPL29P10, RPL29_3_370, ribosomal protein L29
External IDs	OMIM: 601832 HomoloGene: 133570 GeneCards: RPL29
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3p21.2 Start 51,993,522 bp[1] End 51,995,895 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in stromal cell of endometrium skin of abdomen ganglionic eminence right uterine tube subcutaneous adipose tissue canal of the cervix gastrocnemius muscle body of pancreas vagina prostate n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function heparin binding RNA binding structural constituent of ribosome cadherin binding Cellular component intracellular anatomical structure cytosol membrane cytosolic large ribosomal subunit ribosome Biological process translational initiation SRP-dependent cotranslational protein targeting to membrane nuclear-transcribed mRNA catabolic process, nonsense-mediated decay cytoplasmic translation embryo implantation protein biosynthesis viral transcription rRNA processing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6159 n/a Ensembl ENSG00000162244 n/a UniProt P47914 n/a RefSeq (mRNA) NM_000992 n/a RefSeq (protein) NP_000983 n/a Location (UCSC) Chr 3: 51.99 – 52 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

60S ribosomal protein L29 is a protein that in humans is encoded by the RPL29 gene.^[3][4]

Function

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 60S subunit. The protein belongs to the L29E family of ribosomal proteins. The protein is also a peripheral membrane protein expressed on the cell surface that directly binds heparin. Although this gene was previously reported to map to 3q29-qter, it is believed that it is located at 3p21.3-p21.2. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.^[4]

Interactions

RPL29 has been shown to interact with BLMH.^[5]