RPL35
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4UG0, 4V6X, 5AJ0, 4V5Z, 4UJD, 4D67, 4D5Y, 4UJE, 4UJC
Identifiers
Aliases	RPL35, L35, ribosomal protein L35, DBA19
External IDs	OMIM: 618315 MGI: 1913739 HomoloGene: 31432 GeneCards: RPL35
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9q33.3 Start 124,857,880 bp[1] End 124,861,981 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 B Start 38,891,592 bp[2] End 38,895,636 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in skin of abdomen anterior pituitary right uterine tube Achilles tendon body of pancreas canal of the cervix periodontal fiber right lobe of thyroid gland lymph node left lobe of thyroid gland Top expressed in urinary bladder ovary neural tube adrenal gland placenta white adipose tissue bone marrow lip lens uterus More reference expression data BioGPS n/a
Gene ontology Molecular function mRNA binding RNA binding structural constituent of ribosome Cellular component cytosol ribosome membrane intracellular anatomical structure nucleolus cytosolic large ribosomal subunit Biological process viral transcription SRP-dependent cotranslational protein targeting to membrane maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) translational initiation nuclear-transcribed mRNA catabolic process, nonsense-mediated decay rRNA processing protein biosynthesis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 11224 66489 Ensembl ENSG00000136942 ENSMUSG00000062997 UniProt P42766 Q6ZWV7 RefSeq (mRNA) NM_007209 NM_025592 RefSeq (protein) NP_009140 NP_079868 Location (UCSC) Chr 9: 124.86 – 124.86 Mb Chr 2: 38.89 – 38.9 Mb PubMed search [3] [4]
Wikidata
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60S ribosomal protein L35 is a protein that in humans is encoded by the RPL35 gene.^[5][6]

Function

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L29P family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.^[6]