AKR7A3
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 2CLP
Identifiers
Aliases	AKR7A3, AFAR2, aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase), aldo-keto reductase family 7 member A3
External IDs	OMIM: 608477 HomoloGene: 49295 GeneCards: AKR7A3
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p36.13 Start 19,282,573 bp[1] End 19,288,770 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in duodenum jejunal mucosa body of pancreas right lobe of liver pancreatic ductal cell kidney cardia body of stomach gallbladder pylorus n/a More reference expression data BioGPS n/a
Gene ontology Molecular function electron transfer activity oxidoreductase activity aldo-keto reductase (NADP) activity protein binding identical protein binding alditol:NADP+ 1-oxidoreductase activity Cellular component cytoplasm extracellular exosome cytosol Biological process xenobiotic metabolic process cellular aldehyde metabolic process electron transport chain aflatoxin metabolic process aflatoxin catabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 22977 n/a Ensembl ENSG00000162482 n/a UniProt O95154 n/a RefSeq (mRNA) NM_012067 n/a RefSeq (protein) NP_036199 n/a Location (UCSC) Chr 1: 19.28 – 19.29 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Aldo-keto reductase family 7 member A3 is a protein that in humans is encoded by the AKR7A3 gene. ^[3]

Function

Aldo-keto reductases, such as AKR7A3, are involved in the detoxification of aldehydes and ketones.[supplied by OMIM, Apr 2004].