ALDH3B2
Identifiers
Aliases	ALDH3B2, ALDH8, aldehyde dehydrogenase 3 family member B2
External IDs	OMIM: 601917 GeneCards: ALDH3B2
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q13.2 Start 67,662,155 bp[1] End 67,681,224 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in vulva skin of abdomen oral cavity parotid gland human penis nipple vagina hair follicle thymus minor salivary gland n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function 3-chloroallyl aldehyde dehydrogenase activity oxidoreductase activity aldehyde dehydrogenase [NAD(P)+ activity] oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Cellular component lipid droplet Biological process ethanol catabolic process metabolism alcohol metabolic process lipid metabolism sphingolipid biosynthetic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 222 n/a Ensembl ENSG00000132746 n/a UniProt P48448 n/a RefSeq (mRNA) NM_000695 NM_001031615 NM_001354345 NM_001393400 NM_001393401 NM_001393402 n/a RefSeq (protein) NP_000686 NP_001026786 NP_001341274 n/a Location (UCSC) Chr 11: 67.66 – 67.68 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Aldehyde dehydrogenase family 3 member B2 is an enzyme that in humans is encoded by the ALDH3B2 gene.^[3][4][5]

This gene encodes a member of the aldehyde dehydrogenase family, a group of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The gene of this particular family member is over 10 kb in length. The expression of these transcripts is restricted to the salivary gland among the human tissues examined. Alternate transcriptional splice variants have been characterized.^[5]