AP3S1
Identifiers
Aliases	AP3S1, CLAPS3, Sigma3A, adaptor related protein complex 3 sigma 1 subunit, adaptor related protein complex 3 subunit sigma 1
External IDs	OMIM: 601507 MGI: 1337062 HomoloGene: 4254 GeneCards: AP3S1
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5q22.3-q23.1 Start 115,841,481 bp[1] End 115,914,081 bp[1]
Gene location (Mouse) Chr. Chromosome 18 (mouse)[2] Band 18|18 C Start 46,874,943 bp[2] End 46,923,893 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon hippocampus proper superior frontal gyrus amygdala dorsolateral prefrontal cortex nucleus accumbens ascending aorta right coronary artery Brodmann area 9 prefrontal cortex Top expressed in ganglionic eminence thymus white adipose tissue neural tube ileum mesencephalon jejunum ovary pancreas lens More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding transporter activity Cellular component AP-3 adaptor complex membrane coat Golgi apparatus AP-type membrane coat adaptor complex transport vesicle cytoplasmic vesicle membrane intracellular membrane-bounded organelle membrane cytoplasmic vesicle axon cytoplasm Biological process anterograde axonal transport protein transport insulin receptor signaling pathway anterograde synaptic vesicle transport intracellular protein transport vesicle-mediated transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 1176 11777 Ensembl ENSG00000177879 ENSMUSG00000024480 UniProt Q92572 Q9DCR2 RefSeq (mRNA) NM_001002924 NM_001284 NM_001318090 NM_001318091 NM_001318093 NM_001318094 NM_009681 NM_001303015 RefSeq (protein) NP_001002924 NP_001275 NP_001305019 NP_001305020 NP_001305022 NP_001305023 NP_001351048 NP_001351049 NP_001351051 NP_001289944 NP_033811 Location (UCSC) Chr 5: 115.84 – 115.91 Mb Chr 18: 46.87 – 46.92 Mb PubMed search [3] [4]
Wikidata
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AP-3 complex subunit sigma-1 is a protein that in humans is encoded by the AP3S1 gene.^[5][6][7]