ASAH2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4WGK
Identifiers
Aliases	ASAH2, BCDase, HNAC1, LCDase, N-CDase, NCDase, N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2, N-acylsphingosine amidohydrolase 2
External IDs	OMIM: 611202 MGI: 1859310 HomoloGene: 10310 GeneCards: ASAH2
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q11.23 Start 50,182,778 bp[1] End 50,279,720 bp[1]
Gene location (Mouse) Chr. Chromosome 19 (mouse)[2] Band 19|19 C1 Start 31,959,997 bp[2] End 32,085,611 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in duodenum stromal cell of endometrium islet of Langerhans smooth muscle tissue ganglionic eminence thymus skeletal muscle tissue liver fundus Achilles tendon Top expressed in intestinal villus jejunum lacrimal gland duodenum esophagus parotid gland motor neuron medial vestibular nucleus spinal cord ileum More reference expression data BioGPS n/a
Gene ontology Molecular function hydrolase activity ceramidase activity calcium ion binding zinc ion binding N-acylsphingosine amidohydrolase activity metal ion binding Cellular component integral component of membrane plasma membrane membrane mitochondrion extracellular region Biological process lipid metabolism sphingolipid metabolic process apoptotic process sphingosine metabolic process ceramide metabolic process response to organic substance long-chain fatty acid biosynthetic process sphingosine biosynthetic process ceramide catabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 56624 54447 Ensembl ENSG00000188611 ENSMUSG00000024887 UniProt Q9NR71 Q9JHE3 RefSeq (mRNA) NM_001143974 NM_019893 NM_018830 RefSeq (protein) NP_001137446 NP_063946 NP_061300 Location (UCSC) Chr 10: 50.18 – 50.28 Mb Chr 19: 31.96 – 32.09 Mb PubMed search [3] [4]
Wikidata
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Neutral ceramidase is an enzyme that in humans is encoded by the ASAH2 gene.^[5][6]