Protein-coding gene in the species Homo sapiens
Histone chaperone ASF1A is a protein that in humans is encoded by the ASF1A gene.[5][6][7]
Function
This gene encodes a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The protein is a key component of a histone donor complex that functions in nucleosome assembly. It interacts with histones H3 and H4, and functions together with a chromatin assembly factor during DNA replication and repair.[7]
Interactions
ASF1A has been shown to interact with TLK1,[8][9] TLK2,[8] CHAF1B[10] and CHAF1A.[10]