ATC code G: Genito-urinary system and sex hormones
G01 Gynecological antiinfectives and antiseptics G02 Other gynecologicals G03 Sex hormones and modulators of the genital system G04 Urologicals
ATCvet only
QG51 Antiinfectives and antiseptics for intrauterine use QG52 Products for teats and udder
Other ATC codes
A B C D G H QI J L M N P R S V

ATC code G03 Sex hormones and modulators of the genital system is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.^[1]^[2]^[3] Subgroup G03 is part of the anatomical group G Genito-urinary system and sex hormones.^[4]

Codes for veterinary use (ATCvet codes) can be created by placing the letter Q in front of the human ATC code: for example, QG03.^[5] ATCvet codes without corresponding human ATC codes are cited with the leading Q in the following list.
National issues of the ATC classification may include additional codes not present in this list, which follows the WHO version.

G03A Hormonal contraceptives for systemic use

G03AA Progestogens and estrogens, fixed combinations

G03AA01 Etynodiol and ethinylestradiol

G03AA02 Quingestanol and ethinylestradiol

G03AA03 Lynestrenol and ethinylestradiol

G03AA04 Megestrol and ethinylestradiol

G03AA05 Norethisterone and ethinylestradiol

G03AA06 Norgestrel and ethinylestradiol

G03AA07 Levonorgestrel and ethinylestradiol

G03AA08 Medroxyprogesterone and ethinylestradiol

G03AA09 Desogestrel and ethinylestradiol

G03AA10 Gestodene and ethinylestradiol

G03AA11 Norgestimate and ethinylestradiol

G03AA12 Drospirenone and ethinylestradiol

G03AA13 Norelgestromin and ethinylestradiol

G03AA14 Nomegestrol and estradiol

G03AA15 Chlormadinone and ethinylestradiol

G03AA16 Dienogest and ethinylestradiol

G03AA17 Medroxyprogesterone and estradiol

G03AA18 Drospirenone and estetrol

G03AB Progestogens and estrogens, sequential preparations

G03AB01 Megestrol and ethinylestradiol

G03AB02 Lynestrenol and ethinylestradiol

G03AB03 Levonorgestrel and ethinylestradiol

G03AB04 Norethisterone and ethinylestradiol

G03AB05 Desogestrel and ethinylestradiol

G03AB06 Gestodene and ethinylestradiol

G03AB07 Chlormadinone and ethinylestradiol

G03AB08 Dienogest and estradiol

G03AB09 Norgestimate and ethinylestradiol

G03AC Progestogens

G03AC01 Norethisterone

G03AC02 Lynestrenol

G03AC03 Levonorgestrel

G03AC04 Quingestanol

G03AC05 Megestrol

G03AC06 Medroxyprogesterone

G03AC07 Norgestrienone

G03AC08 Etonogestrel

G03AC09 Desogestrel

G03AC10 Drospirenone

G03AD Emergency contraceptives

G03AD01 Levonorgestrel

G03AD02 Ulipristal

G03B Androgens

G03BA 3-oxoandrosten-(4) derivatives

G03BA01 Fluoxymesterone

G03BA02 Methyltestosterone

G03BA03 Testosterone

G03BB 5-androstanon-(3) derivatives

G03BB01 Mesterolone

G03BB02 Androstanolone

G03C Estrogens

G03CA Natural and semisynthetic estrogens, plain

G03CA01 Ethinylestradiol

G03CA03 Estradiol

G03CA04 Estriol

G03CA06 Chlorotrianisene

G03CA07 Estrone

G03CA09 Promestriene

G03CA53 Estradiol, combinations

G03CA57 Conjugated estrogens

G03CB Synthetic estrogens, plain

G03CB01 Dienestrol

G03CB02 Diethylstilbestrol

G03CB03 Methallenestril

G03CB04 Moxestrol

G03CC Estrogens, combinations with other drugs

G03CC02 Dienestrol

G03CC03 Methallenestril

G03CC04 Estrone

G03CC05 Diethylstilbestrol

G03CC06 Estriol

G03CC07 Conjugated estrogens and bazedoxifene

G03CX Other estrogens

G03CX01 Tibolone

G03D Progestogens

G03DA Pregnen-(4) derivatives

G03DA01 Gestonorone

G03DA02 Medroxyprogesterone

G03DA03 Hydroxyprogesterone

G03DA04 Progesterone

QG03DA90 Proligestone

G03DB Pregnadien derivatives

G03DB01 Dydrogesterone

G03DB02 Megestrol

G03DB03 Medrogestone

G03DB04 Nomegestrol

G03DB05 Demegestone

G03DB06 Chlormadinone

G03DB07 Promegestone

G03DB08 Dienogest

G03DC Estren derivatives

G03DC01 Allylestrenol

G03DC02 Norethisterone

G03DC03 Lynestrenol

G03DC04 Ethisterone

G03DC05 Tibolone

G03DC06 Etynodiol

G03DC31 Methylestrenolone (normethandrone)

QG03DX Other progestogens

QG03DX90 Altrenogest

QG03DX91 Delmadinone

G03E Androgens and female sex hormones in combination

G03EA Androgens and estrogens

G03EA01 Methyltestosterone and estrogen

G03EA02 Testosterone and estrogen

G03EA03 Prasterone and estrogen

G03EB Androgen, progestogen and estrogen in combination

G03EK Androgens and female sex hormones in combination with other drugs

G03EK01 Methyltestosterone

G03F Progestogens and estrogens in combination

G03FA Progestogens and estrogens, fixed combinations

G03FA01 Norethisterone and estrogen

G03FA02 Hydroxyprogesterone and estrogen

G03FA03 Ethisterone and estrogen

G03FA04 Progesterone and estrogen

G03FA05 Methylnortestosterone (normethandrone) and estrogen

G03FA06 Etynodiol and estrogen

G03FA07 Lynestrenol and estrogen

G03FA08 Megestrol and estrogen

G03FA09 Noretynodrel and estrogen

G03FA10 Norgestrel and estrogen

G03FA11 Levonorgestrel and estrogen

G03FA12 Medroxyprogesterone and estrogen

G03FA13 Norgestimate and estrogen

G03FA14 Dydrogesterone and estrogen

G03FA15 Dienogest and estrogen

G03FA16 Trimegestone and estrogen

G03FA17 Drospirenone and estrogen

G03FB Progestogens and estrogens, sequential preparations

G03FB01 Norgestrel and estrogen

G03FB02 Lynestrenol and estrogen

G03FB03 Chlormadinone and estrogen

G03FB04 Megestrol and estrogen

G03FB05 Norethisterone and estrogen

G03FB06 Medroxyprogesterone and estrogen

G03FB07 Medrogestone and estrogen

G03FB08 Dydrogesterone and estrogen

G03FB09 Levonorgestrel and estrogen

G03FB10 Desogestrel and estrogen

G03FB11 Trimegestone and estrogen

G03FB12 Nomegestrol and estrogen

G03G Gonadotropins and other ovulation stimulants

G03GA Gonadotropins

G03GA01 Human chorionic gonadotropin

G03GA02 Human menopausal gonadotropin

G03GA03 Serum gonadotropin

G03GA04 Urofollitropin

G03GA05 Follitropin alfa

G03GA06 Follitropin beta

G03GA07 Lutropin alfa

G03GA08 Choriogonadotropin alfa

G03GA09 Corifollitropin alfa

G03GA10 Follitropin delta

G03GA30 Combinations

QG03GA90 Follicle stimulating hormone-pituitary

QG03GA99 Gonadotropins, combinations

G03GB Ovulation stimulants, synthetic

G03GB01 Cyclofenil

G03GB02 Clomifene

G03GB03 Epimestrol

G03H Antiandrogens

G03HA Antiandrogens, plain

G03HA01 Cyproterone

G03HB Antiandrogens and estrogens

G03HB01 Cyproterone and estrogen

G03X Other sex hormones and modulators of the genital system

G03XA Antigonadotropins and similar agents

G03XA01 Danazol

G03XA02 Gestrinone

QG03XA90 Anti-Pmsg

QG03XA91 Gonadotropin releasing factor analogue, conjugated

G03XB Progesterone receptor modulators

G03XB01 Mifepristone

G03XB02 Ulipristal

G03XB51 Mifepristone, combinations

QG03XB90 Aglepristone

G03XC Selective estrogen receptor modulators

G03XC01 Raloxifene

G03XC02 Bazedoxifene

G03XC03 Lasofoxifene

G03XC04 Ormeloxifene

G03XC05 Ospemifene

G03XX Other sex hormones and modulators of the genital system

G03XX01 Prasterone

QG03XX90 Finrozole

References

^ "ATC (Anatomical Therapeutic Chemical Classification System) – Synopsis". National Institutes of Health. Retrieved 1 February 2020.
^ World Health Organization. "Anatomical Therapeutic Chemical (ATC) Classification". World Health Organization. Retrieved 3 January 2022.
^ "Structure and principles". WHO Collaborating Centre for Drug Statistics Methodology. 15 February 2018. Retrieved 3 January 2022.
^ "ATC/DDD Index 2022: code G03". WHO Collaborating Centre for Drug Statistics Methodology.
^ "ATCvet Index 2022: code QG03". WHO Collaborating Centre for Drug Statistics Methodology.

Birth control methods (G02B, G03A)

Comparison

Behavioral

Avoiding vaginal intercourse	Abstinence Anal sex Masturbation Non-penetrative sex Oral sex
Including vaginal intercourse	Lactational amenorrhea method (LAM) Calendar-based methods Fertility awareness Billings ovulation method Creighton Model Withdrawal

Barrier and / or spermicidal

Hormonal
(formulations)

Combined estrogen–progestogen	Contraceptive patch Extended cycle Injectable Combined vaginal ring Pill
Progestogen-only	Depo-Provera Etonogestrel Levonorgestrel Progestogen-only pill Progesterone vaginal ring

Anti-estrogen

Ormeloxifene (Centchroman)

Post-intercourse

Intrauterine device

Sterilization

Female	Essure Tubal ligation
Male	Vasectomy

Experimental

Reversible inhibition of sperm under guidance

Long-acting reversible contraception (LARC)

Androgens and antiandrogens

Androgens
(incl. AAS)

AR agonists

Testosterone derivatives: Androstenediol dipropionate
Boldenone undecylenate
Clostebol
Clostebol acetate
Clostebol caproate
Clostebol propionate
Cloxotestosterone acetate
Prasterone (dehydroepiandrosterone, DHEA)
Prasterone enanthate (DHEA enanthate)
Prasterone sulfate (DHEA sulfate)
Quinbolone
Testosterone^#
Testosterone esters (e.g., testosterone cypionate, testosterone enanthate, testosterone propionate, testosterone undecanoate, testosterone ester mixtures (Deposterona, Omnadren, Sustanon, Testoviron Depot))

Dihydrotestosterone derivatives: Androstanolone (stanolone, dihydrotestosterone, DHT)
Androstanolone esters
Bolazine capronate
Drostanolone propionate (dromostanolone propionate)
Epitiostanol
Mepitiostane
Mesterolone
Metenolone acetate (methenolone acetate)
Metenolone enanthate (methenolone enanthate)
Stenbolone acetate

19-Nortestosterone derivatives: Bolandiol dipropionate
Nandrolone esters (e.g., nandrolone decanoate, nandrolone phenylpropionate)
Norclostebol
Norclostebol acetate
Oxabolone cipionate (oxabolone cypionate)
Trenbolone acetate
Trenbolone hexahydrobenzylcarbonate (trenbolone cyclohexylmethylcarbonate)

17α-Alkylated testosterone derivatives: Bolasterone
Calusterone
Chlorodehydromethyltestosterone (CDMT)
Fluoxymesterone
Formebolone
Metandienone (methandienone, methandrostenolone)
Methandriol (methylandrostenediol)
Methandriol bisenanthoyl acetate
Methandriol dipropionate
Methandriol propionate
Methyltestosterone
Methyltestosterone 3-hexyl ether
Oxymesterone
Penmesterol
Tiomesterone (thiomesterone)

17α-Alkylated dihydrotestosterone derivatives: Androisoxazole
Furazabol
Mebolazine (dimethazine)
Mestanolone
Oxandrolone
Oxymetholone
Stanozolol

17α-Alkylated 19-nortestosterone derivatives: Ethylestrenol
Mibolerone
Norethandrolone
Normethandrone (methylestrenolone, normethisterone)
Propetandrol (propethandrol)

17α-Vinyltestosterone derivatives: Norvinisterone (vinylnortestosterone)

17α-Ethynyltestosterone derivatives: Danazol
Gestrinone
Progestins (e.g., ethisterone (ethynyltestosterone), levonorgestrel, norgestrel, norethisterone (norethindrone), lynestrenol, norgestrienone)
Tibolone

Progesterone derivatives: Medroxyprogesterone acetate

Progonadotropins

Antiestrogens (e.g., tamoxifen, clomifene)
GnRH agonists (e.g., GnRH (gonadorelin), leuprorelin)
Gonadotropins (e.g., LHTooltip luteinizing hormone, hCGTooltip human chorionic gonadotropin)

Antiandrogens

AR antagonists

Steroidogenesis
inhibitors

5α-Reductase	Alfatradiol Dutasteride Epristeride Finasteride Saw palmetto extract
Others	Abiraterone acetate +niraparib Aminoglutethimide Bifluranol Cyproterone acetate Flutamide Ketoconazole Nilutamide Seviteronel^† Spironolactone

Antigonadotropins

D₂ receptor antagonists (prolactin releasers) (e.g., domperidone, metoclopramide, risperidone, haloperidol, chlorpromazine, sulpiride)
Estrogens (e.g., bifluranol, diethylstilbestrol, estradiol, estradiol esters, ethinylestradiol, ethinylestradiol sulfonate, paroxypropione)
GnRH agonists (e.g., leuprorelin)
GnRH antagonists (e.g., cetrorelix)
Progestogens (incl., chlormadinone acetate, cyproterone acetate, hydroxyprogesterone caproate, gestonorone caproate, medroxyprogesterone acetate, megestrol acetate)

Others

Androstenedione immunogens: Androvax (androstenedione albumin)
Ovandrotone albumin (Fecundin)

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

See also: Androgen receptor modulators; Estrogens and antiestrogens; Progestogens and antiprogestogens; List of androgens/anabolic steroids

Estrogens and antiestrogens

Estrogens

ER agonists

Steroidal: Alfatradiol
Certain androgens/anabolic steroids (e.g., testosterone, testosterone esters, methyltestosterone, metandienone, nandrolone esters) (via estrogenic metabolites)
Certain progestins (e.g., norethisterone, noretynodrel, etynodiol diacetate, tibolone)
Clomestrone
Cloxestradiol acetate
Conjugated estriol
Conjugated estrogens
Epiestriol
Epimestrol
Esterified estrogens
Estetrol^†
Estradiol
Estradiol esters (e.g., estradiol acetate, estradiol benzoate, estradiol cypionate, estradiol enanthate, estradiol undecylate, estradiol valerate, polyestradiol phosphate, estradiol ester mixtures (Climacteron))
Estramustine phosphate
Estriol
Estriol esters (e.g., estriol succinate, polyestriol phosphate)
Estrogenic substances
Estrone
Estrone esters
- Estrone sulfate
- Estropipate (piperazine estrone sulfate)
Ethinylestradiol^#
- Ethinylestradiol sulfonate
Hydroxyestrone diacetate
Mestranol
Methylestradiol
Moxestrol
Nilestriol
Prasterone (dehydroepiandrosterone; DHEA)
- Prasterone enanthate
- Prasterone sulfate
Promestriene
Quinestradol
Quinestrol

Progonadotropins

Antiandrogens (e.g., bicalutamide)
GnRH agonists (e.g., GnRH (gonadorelin), leuprorelin)
Gonadotropins (e.g., FSHTooltip follicle-stimulating hormone, LHTooltip luteinizing hormone)

Antiestrogens

ERTooltip Estrogen receptor antagonists (incl. SERMsTooltip selective estrogen receptor modulators/SERDsTooltip selective estrogen receptor downregulators)	Acolbifene^† Anordrin Bazedoxifene Broparestrol Clomifene^# Cyclofenil Enclomifene^† Epitiostanol Lasofoxifene Mepitiostane Ormeloxifene Ospemifene Raloxifene Tamoxifen^# Toremifene Exclusively antagonistic: Elacestrant Fulvestrant Noncompetitive inhibitors: Trilostane
Aromatase inhibitors	First-generation: Aminoglutethimide Testolactone Second-generation: Fadrozole Formestane Third-generation: Anastrozole Exemestane Letrozole
Antigonadotropins	Androgens/anabolic steroids (e.g., testosterone, testosterone esters, nandrolone esters, oxandrolone, fluoxymesterone) D₂ receptor antagonists (prolactin releasers) (e.g., domperidone, metoclopramide, risperidone, haloperidol, chlorpromazine, sulpiride) GnRH agonists (e.g., leuprorelin, goserelin) GnRH antagonists (e.g., cetrorelix, elagolix) Progestogens (e.g., chlormadinone acetate, cyproterone acetate, gestonorone caproate, hydroxyprogesterone caproate, medroxyprogesterone acetate, megestrol acetate)
Others	Mixed mechanism of action: Danazol Gestrinone Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin)

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

See also: Estrogen receptor modulators; Androgens and antiandrogens; Progestogens and antiprogestogens; List of estrogens

Progestogens and antiprogestogens

Progestogens
(and progestins)

PR agonists

Progesterone derivatives: Progesterone
Quingestrone

Retroprogesterone derivatives: Dydrogesterone
Trengestone

17α-Hydroxyprogesterone (and closely related) derivatives: 17α-Hydroxylated: Acetomepregenol (mepregenol diacetate)
Algestone acetophenide (dihydroxyprogesterone acetophenide)
Anagestone acetate
Chlormadinone acetate
Chlormethenmadinone acetate
Cyproterone acetate
Delmadinone acetate
Flugestone acetate (flurogestone acetate)
Flumedroxone acetate
Hydroxyprogesterone acetate
Hydroxyprogesterone caproate
Hydroxyprogesterone heptanoate
Medroxyprogesterone acetate^#
Megestrol acetate
Melengestrol acetate
Methenmadinone acetate
Osaterone acetate
Pentagestrone acetate
Proligestone; 17α-Methylated: Medrogestone; Others: Haloprogesterone

19-Norprogesterone derivatives: 17α-Hydroxylated: Gestonorone caproate (gestronol hexanoate)
Nomegestrol acetate
Norgestomet
Segesterone acetate (nestorone, elcometrine); 17α-Methylated: Demegestone
Promegestone
Trimegestone

Testosterone derivatives: Estranes: Danazol
Dimethisterone
Ethisterone

19-Nortestosterone derivatives: Estranes: Allylestrenol
Altrenogest
Dienogest
Etynodiol diacetate
Lynestrenol
Norethisterone (norethindrone)^#
Norethisterone acetate
Norethisterone enanthate
Noretynodrel
Norgesterone
Norgestrienone
Normethandrone (methylestrenolone)
Norvinisterone
Oxendolone
Quingestanol acetate
Tibolone; Gonanes: Desogestrel
Etonogestrel
Gestodene
Gestrinone
Levonorgestrel^#
Norelgestromin
Norgestimate
Norgestrel

Spirolactone derivatives: Drospirenone

Others: Anabolic–androgenic steroids (e.g., nandrolone and esters, trenbolone and esters, ethylestrenol, norethandrolone, others)

Antiprogestogens

SPRMsTooltip Selective progesterone receptor modulators	Telapristone^§ Ulipristal acetate
PRTooltip Progesterone receptor antagonists	Aglepristone Mifepristone

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

See also: Progesterone receptor modulators; Androgens and antiandrogens; Estrogens and antiestrogens; List of progestogens

GnRH and gonadotropins

GnRH modulators
(incl. analogues)

Agonists	Peptide: Azagly-nafarelin Buserelin Deslorelin Fertirelin Gonadorelin Goserelin Histrelin Lecirelin Leuprorelin (leuprolide) Nafarelin Peforelin Triptorelin
Antagonists	Peptide: Abarelix Cetrorelix Degarelix Ganirelix Non-peptide: Elagolix Linzagolix^† Relugolix (+estradiol/norethisterone acetate)

Gonadotropins

Preparations	Follicle-stimulating hormone Human chorionic gonadotropin Luteinizing hormone Menotropin Urofollitropin

Others
(indirect)

Progonadotropins

Sex steroid antagonists (via disinhibition of the HPG axis): Antiandrogens (e.g., flutamide, bicalutamide, enzalutamide)
Antiestrogens/SERMsTooltip Selective estrogen receptor modulators (e.g., tamoxifen, clomifene, enclomifene)
Aromatase inhibitors (e.g., anastrozole)
GnRH agonists (e.g., GnRHTooltip gonadotropin-releasing hormone)

Antigonadotropins

Sex steroid agonists (via negative feedback on the HPG axis): Androgens/anabolic steroids (e.g., testosterone, nandrolone esters, oxandrolone)
D₂ receptor antagonists (prolactin releasers) (incl., domperidone, metoclopramide, risperidone, haloperidol, chlorpromazine, sulpiride)
Estrogens (incl., bifluranol, estradiol, estradiol esters, ethinylestradiol, diethylstilbestrol, paroxypropione)
Progestogens (incl. progestins, e.g., chlormadinone acetate, cyproterone acetate, hydroxyprogesterone caproate, gestonorone caproate, medroxyprogesterone acetate, megestrol acetate)

Others (mixed or unknown mechanism of action): Danazol
Gestrinone
Metallibure

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

See also: GnRH and gonadotropin receptor modulators; Androgens and antiandrogens; Estrogens and antiestrogens; Progestogens and antiprogestogens