Aaron Diamond AIDS Research Center, often abbreviated as ADARC, is a medical research institution dedicated to finding a cure for HIV/AIDS. It is headed by scientist Dr. David Ho, who was the 1996 Time magazine Person of the Year, and is located in New York City.[1]

Opening in 1991, the center was the brainchild of the Aaron Diamond Foundation headed by his widow Irene Diamond, the New York City Department of Health, the Public Health Research Institute and New York University School of Medicine. It became affiliated with Rockefeller University in 1996, and became part of Columbia University's medical school, Columbia University Vagelos College of Physicians and Surgeons, in 2019.[2][3]

One is the introduction of combination antiretroviral therapy[4] to combat HIV drug resistance[4][5] and hence prevent[6] progression to fatal full-blown AIDS. David Ho and his team presented their remarkable clinical trial results at the International AIDS Conference 1996.[7] This marked a turning point in which HIV infection was no longer an absolute terminal disease but a manageable chronic disease.[8]

References

  1. ^ Park, Alice (25 January 2010). "Scientist David Ho: The Man Who Could Beat AIDS". Time. Archived from the original on June 4, 2011. Retrieved 24 January 2010.
  2. ^ "Aaron Diamond AIDS Research Center to Join Columbia University". 19 March 2019. Archived from the original on 7 June 2023.
  3. ^ "Aaron Diamond AIDS Research Center will end 23-year affiliation with Rockefeller". 2019-03-20. Archived from the original on 2022-12-08.
  4. ^ a b Ho, David (August 17, 1995). "Time to Hit HIV, Early and Hard". New England Journal of Medicine. 333 (7): 450–451. doi:10.1056/NEJM199508173330710. PMID 7616996. Archived from the original on September 1, 2015. Retrieved January 29, 2023. ... zidovudine was shown in 1990 to slow the clinical progression to AIDS in infected but asymptomatic subjects. However, a follow-up of those subjects found no evidence of longer survival with the use of zidovudine...
  5. ^
  6. ^
    • "Interviews - David Ho - The Age Of Aids - Frontline". Frontline. PBS. May 30, 2006. Archived from the original on March 7, 2007. Retrieved January 29, 2023. ... if you start to combine the drugs and try to force the virus into a corner using multiple drugs, it is exceedingly difficult or statistically improbable for HIV to become resistant to all the drugs simultaneously.
    • "The Age of AIDS, Part II". Frontline. Season 24 (2006). Episode 11. 2006-05-31. Event occurs at 0:18:54. PBS. Retrieved 2023-01-31. ... However, if you start to combine the drugs and try to force the virus into a corner using multiple drugs, it is exceedingly difficult...for HIV to become resistant to all the drugs simultaneously. 
  7. ^ "The Age of AIDS, Part II". Frontline. Season 24 (2006). Episode 11. 2006-05-31. Event occurs at 0:21:50. PBS. Retrieved 2023-01-31. International AIDS Conference 1996 in Vancouver showing combination therapy results
  8. ^ Mahungu, Tabitha; Rodger, Alison; Johnson, Margaret (2009-04-01). "HIV as a chronic disease". Clinical Medicine. 9 (2): 125–128. doi:10.7861/clinmedicine.9-2-125. PMC 4952661. PMID 19435115. Archived from the original on 2020-07-23. Retrieved 2023-01-31.

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