Ghanaian scientist
Abraham Badu-Tawiah is a Ghanaian scientist who is an Associate Professor of Chemistry at the Ohio State University. His research considers the development of mass spectrometry for the detection of disease. In 2017 he was awarded the American Chemical Society Arthur F. Findeis prize and in 2020 a Sloan Research Fellowship.
Early life and education
Badu-Tawiah is from rural Ghana.[1] He was one of three graduates of a high school class of 500 that went on to attend university.[1] He earned his bachelor's and master's degree at the Kwame Nkrumah University of Science and Technology.[2] In 2005 he moved to the United States, where he joined the laboratory of R. Graham Cooks at Purdue University to study high-performance liquid chromatography.[3][4] There he studied reactions in mass spectrometers, and started to investigate whether this unique environment could be used for synthesis.[1] Whilst at Purdue, Badu-Tawiah was awarded several research fellowships, including the Andrews and Lilly Innovation Fellowships.[2][5] In 2012 Badu-Tawiah joined Harvard University where he worked in the research laboratory of George M. Whitesides. There he developed paper-based systems capable of performing molecular recognition.[5] In particular, Badu-Tawiah looked to develop macrofluidic platforms that could analyse for specific biomarkers.[1] Unfortunately, the enzymes required to detect biomarkers on paper-based platforms are not stable and require careful storage.[1]
Research and career
Badu-Tawiah was appointed assistant professor at the Ohio State University in 2014.[6] His research considers new mass spectrometry techniques for the detection of disease. Mass spectrometry offers several advantages over macrofluidic platforms, as they remain stable.[1] To achieve this he makes use of cleavable ionic probes that can be used to perform immunoassays.[5] These probes can be attached to antibodies and mounted to a flexible substrate for screening without refrigeration.[1] He made use of wax ink to trace out the outline of the channels of the device, forming a waterproof barrier that separates that safely captures and stores the blood sample.[7] Badu-Tawiah has worked on devices that can allow the early-detection of malaria and Zika virus.[1] In 2016 he demonstrated that these simple diagnostic tests were able to accurately diagnose whether someone was infected with malaria up to one month after blood was collected, and that patients could send them by mail to research labs.[7] Alongside malaria diagnosis, the tests are capable of identifying the cancer antigens that are markers for cancers of the large intestine.[7][8]
Alongside disease detection, Badu-Tawiah works on novel analytical devices for photo- and electro-catalytic screening.[1][5]
