|Chemical and physical data|
|Molar mass||369.513 g·mol−1|
|3D model (JSmol)|
|NY (what is this?)|
Adatanserin (WY-50,324, SEB-324) is a mixed 5-HT1A receptor partial agonist and 5-HT2A and 5-HT2C receptor antagonist. It was under development by Wyeth as an antidepressant but was ultimately not pursued.
Adantaserin has been shown to be neuroprotective against ischemia-induced glutamatergic excitotoxicity, an effect which appears to be mediated by blockade of the 5-HT2A receptor.
(no additional rings)
(piperazine attached via side chain)