Algestone acetonide
Clinical data
Other namesW-3395; Alfasone acetonide; Alphasone acetonide; Algestone 16α,17α-acetonide; 16α,17α-Isopropylidenedioxyprogesterone; 16α,17α-(Isopropylidenedioxy)pregn-4-ene-3,20-dione
Drug classProgestin; Progestogen
Identifiers
  • (1R,2S,4R,8S,9S,12S,13R)-8-acetyl-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icos-17-en-16-one
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.023.280 Edit this at Wikidata
Chemical and physical data
FormulaC24H34O4
Molar mass386.532 g·mol−1
3D model (JSmol)
  • CC(=O)[C@@]12[C@@H](C[C@@H]3[C@@]1(CC[C@H]4[C@H]3CCC5=CC(=O)CC[C@]45C)C)OC(O2)(C)C
  • InChI=1S/C24H34O4/c1-14(25)24-20(27-21(2,3)28-24)13-19-17-7-6-15-12-16(26)8-10-22(15,4)18(17)9-11-23(19,24)5/h12,17-20H,6-11,13H2,1-5H3/t17-,18+,19+,20-,22+,23+,24-/m1/s1
  • Key:LSWBQIAZNGURQV-WTBIUSKOSA-N

Algestone acetonide (developmental code name W-3395), also known as algestone 16α,17α-acetonide or 16α,17α-isopropylidenedioxyprogesterone, is a progestin which was never marketed.[1][2] It is the acetonide cyclic ketal of algestone.[1][2] Another progestin, algestone acetophenide, in contrast, has been marketed.[1][2]

Chemistry

See also: List of progestogens and List of progestogen esters § Cyclic ketals of progesterone derivatives

References

  1. ^ a b c Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 27–. ISBN 978-1-4757-2085-3.
  2. ^ a b c Morton IK, Hall JM (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 10–. ISBN 978-94-011-4439-1.


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