Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

α-Endopsychosin is an antagonist of the phencyclidine site of the NMDA receptor which was discovered in extracts of porcine brain and may also be endogenous in humans.[1][2][3] The compound appears to be a peptide, but has yet to be purified and fully characterized.[1][3]

See also


  1. ^ a b Contreras PC, DiMaggio DA, O'Donohue TL (1985). "Evidence for an endogenous peptide ligand and antagonist for PCP receptors". Prog. Clin. Biol. Res. 192: 495–8. PMID 3001770.
  2. ^ John Calvin M. Brust (2004). Neurological Aspects of Substance Abuse. Butterworth-Heinemann. pp. 296–. ISBN 978-0-7506-7313-6.
  3. ^ a b Allan Tasman; Stephen M. Goldfinger (1991). American Psychiatric Press Review of Psychiatry. American Psychiatric Pub. pp. 494–. ISBN 978-0-88048-436-7.