TTPA
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1OIP, 1OIZ, 1R5L
Identifiers
Aliases	TTPA, ATTP, AVED, TTP1, alphaTTP, tocopherol (alpha) transfer protein, alpha tocopherol transfer protein
External IDs	OMIM: 600415 MGI: 1354168 HomoloGene: 37295 GeneCards: TTPA
Gene location (Human) Chr. Chromosome 8 (human)[1] Band 8q12.3 Start 63,048,553 bp[1] End 63,086,053 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4 A3|4 7.76 cM Start 20,007,938 bp[2] End 20,030,785 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of liver rectum nucleus accumbens caudate nucleus amygdala putamen ganglionic eminence cingulate gyrus Brodmann area 9 prefrontal cortex Top expressed in left lobe of liver parotid gland submandibular gland hair follicle proximal tubule mammary gland sexually immature organism kidney lacrimal gland substantia nigra More reference expression data BioGPS More reference expression data
Gene ontology Molecular function vitamin binding vitamin E binding phosphatidylinositol-3,4-bisphosphate binding protein binding phosphatidylinositol-4,5-bisphosphate binding lipid binding lipid transfer activity Cellular component cytoplasm late endosome cytosol Biological process intracellular pH reduction response to nutrient placenta development lipid metabolism embryonic placenta development negative regulation of cell death negative regulation of establishment of blood-brain barrier response to pH vitamin transport response to toxic substance vitamin E metabolic process intermembrane lipid transfer developmental process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7274 50500 Ensembl ENSG00000137561 ENSMUSG00000073988 UniProt P49638 Q8BWP5 RefSeq (mRNA) NM_000370 NM_015767 NM_001317723 RefSeq (protein) NP_000361 NP_001304652 NP_056582 Location (UCSC) Chr 8: 63.05 – 63.09 Mb Chr 4: 20.01 – 20.03 Mb PubMed search [3] [4]
Wikidata
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Alpha-tocopherol transfer protein (α-TTP) is a protein that in humans is encoded by the TTPA gene.^[5][6][7]