Amflutizole
Clinical data
ATC code
  • none
Identifiers
  • 4-Amino-3-[3-(trifluoromethyl)phenyl]-1,2-thiazole-5-carboxylic acid
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC11H7F3N2O2S
Molar mass288.24 g·mol−1
3D model (JSmol)
  • FC(F)(F)c1cccc(c1)c2nsc(c2N)C(=O)O
  • InChI=1S/C11H7F3N2O2S/c12-11(13,14)6-3-1-2-5(4-6)8-7(15)9(10(17)18)19-16-8/h1-4H,15H2,(H,17,18) checkY
  • Key:KVMCEGAWQYTFKC-UHFFFAOYSA-N checkY
  (verify)

Amflutizole is a xanthine oxidase inhibitor[1] used for the treatment of gout.

References

[edit]
  1. ^ O'Regan MH, Smith-Barbour M, Perkins LM, Cao X, Phillis JW (October 1994). "The effect of amflutizole, a xanthine oxidase inhibitor, on ischemia-evoked purine release and free radical formation in the rat cerebral cortex". Neuropharmacology. 33 (10): 1197–201. doi:10.1016/S0028-3908(05)80010-3. PMID 7862255. S2CID 37262919.
Receptor
(ligands)
P0 (adenine)
P1
(adenosine)
P2
(nucleotide)
P2X
(ATPTooltip Adenosine triphosphate)
P2Y
Transporter
(blockers)
CNTsTooltip Concentrative nucleoside transporters
ENTsTooltip Equilibrative nucleoside transporters
PMATTooltip Plasma membrane monoamine transporter
Enzyme
(inhibitors)
XOTooltip Xanthine oxidase
Others
Others
Categories