Amlodipine/olmesartan
Combination of
AmlodipineCalcium channel blocker
OlmesartanAngiotensin II antagonist
Clinical data
Trade namesAzor, Sevikar
Other namesOlmesartan/amlodipine
AHFS/Drugs.comMicromedex Detailed Consumer Information
License data
Pregnancy
category
Routes of
administration		By mouth
ATC code
Legal status
Legal status
Identifiers
CAS Number
KEGG

Amlodipine/olmesartan, sold under the brand name Azor, among others is a fixed-dose combination medication used to treat high blood pressure.[5] It contains amlodipine, as the besilate, a dihydropyridine calcium channel blocker, and olmesartan medoxomil, an angiotensin II receptor blocker.[5]

Amlodipine/olmesartan was approved for medical use in the United States in September 2007.[5][7] It is available as a generic medication.

Medical uses

The combination is indicated for the treatment of hypertension, alone or with other antihypertensive agents, to lower blood pressure.[5]

History

The combination has been studied in clinical trials; one test showed it reduced blood pressure during a 24-hour period and was well tolerated.[8]

References

  1. ^ "TGA eBS - Product and Consumer Medicine Information Licence". www.ebs.tga.gov.au.
  2. ^ "OLAMLO, OLMAKAR, OLMESARTAN/AMLODIPINE ASTRON, OLMESARTAN/AMLODIPINE INTAS (Accord Healthcare Pty Ltd)". Department of Health and Aged Age. Retrieved 3 April 2023.
  3. ^ "SEVIKAR 20/5 olmesartan medoxomil / amlodipine (as besilate) 20/5 mg tablet blister pack (157565)". Therapeutic Goods Administration (TGA). 27 May 2022. Retrieved 3 April 2023.
  4. ^ "Sevikar 20 mg/5 mg Film-Coated Tablets - Summary of Product Characteristics (SmPC)". (emc). 11 July 2022. Retrieved 19 March 2023.
  5. ^ a b c d e "Azor- amlodipine besylate and olmesartan medoxomil tablet, film coated". DailyMed. 7 September 2022. Retrieved 17 March 2023.
  6. ^ "Azor- amlodipine besylate and olmesartan medoxomil tablet, film coated". DailyMed. 7 June 2022. Retrieved 18 March 2023.
  7. ^ "Drug Approval Package: Azor (amlodipine and olmesartan medoxomil) NDA #022100". U.S. Food and Drug Administration (FDA). 17 December 2009. Retrieved 17 March 2023.
  8. ^ Alexander W (June 2009). "American society of hypertension and american urological association". P & T. Pharmacy & Therapeutics. 34 (6): 318–21. PMC 2697919. PMID 19572050.

External links

Antihypertensive drugs acting on the renin–angiotensin system (C09)
Ion channel modulators
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