Andrew Lewis may refer to:

Law and politics

• Sir Andrew J. W. Lewis (1875-1952), Scottish businessman and politician; Lord Provost of Aberdeen
• Andrew L. Lewis Jr. (1931–2016), American railroad executive and US Secretary of Transportation
• Andrew Lewis (Pennsylvania politician) (born 1987), American politician in the Pennsylvania House of Representatives
• Andrew J. Lewis (politician) (born 1989), American politician on the Seattle City Council
• Andrew Lewis (professor), English legal scholar and professor at University College London

Military

• Andrew Lewis (soldier) (1720–1781), American pioneer, surveyor, and soldier
• Andrew Lewis (Royal Navy officer) (1918–1994), British admiral
• Andrew L. Lewis (admiral) (born 1963), US Navy admiral

Sports

• Andrew Lewis (boxer) (1970–2015), Guyanese boxer
• Andrew Lewis (rugby union) (born 1973), Welsh international rugby union player
• Andrew Lewis (soccer) (born 1974), American soccer player
• Andrew Lewis (sailor) (born 1989), Trinidadian sailor

Others

• Andrew W. Lewis (1943–2017), American historian at Missouri State University
• Andrew Lewis (composer) (born 1963), British composer
• Andrew J. Lewis (comics), British comics writer

Other uses

• Andrew Lewis High School, Salem, Virginia