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Antonios G. Mikos
BornDecember 30, 1960
Thessaloniki, Greece
Alma materAristotle University of Thessaloniki, Purdue University
Known forBiomaterials science
AwardsActa Biomaterialia Gold Medal (2019), Lifetime Achievement Award, Tissue Engineering and Regenerative Medicine International Society-Americas (2015), Founders Award, Society For Biomaterials (2011), Robert A. Pritzker Distinguished Lecturer Award, Biomedical Engineering Society (2007)
Scientific career
FieldsBioengineering, Chemical and Biomolecular Engineering
InstitutionsRice University
Doctoral advisorNicholas A. Peppas
Other academic advisorsRobert S. Langer, Joseph P. Vacanti
Websitehttp://mikoslab.rice.edu/

Antonios Georgios Mikos (born 1960)[1] is a Greek-American biomedical engineer who is the Louis Calder Professor of Bioengineering and Chemical and Biomolecular Engineering at Rice University.[2][3] He specialises in biomaterials, drug delivery, and tissue engineering.[4][5]

Education

Mikos completed undergraduate study in engineering at the Aristotle University of Thessaloniki (Dipl. Eng., 1983), and pursued a master's and doctorate (M.S. in chemical engineering, 1985 and Ph.D. in chemical engineering, 1988) at Purdue University in the United States.[6][5] After his doctoral studies, he performed his postdoctoral work at Massachusetts Institute of Technology and the Harvard Medical School.[6][4][5]

Career

Mikos is the Louis Calder Professor of Bioengineering and Chemical and Biomolecular Engineering at Rice University in Houston, Texas.[4][5] He is also the Director of the National Institutes of Health Center for Engineering Complex Tissues, Director of the Center for Excellence in Tissue Engineering, and Director of the John W. Cox Laboratory of Biomedical Engineering at Rice University.[4][5]

Mikos’ research centers on developing biomaterial systems for tissue engineering, drug delivery, gene delivery, and disease modeling.[4] His has studied cartilage,[7] bone,[8] muscle,[9][10][11] and cardiovascular[12] engineering, controlled release platforms for growth factors,[13] non-viral vectors,[14] and scaffolds for studying tumor microenvironments.[15] In 2021, he began studying 3D printing for tissue engineering and hydrogel systems for bone and cartilage regeneration.[16][17][18]

He co-authored a textbook entitled Biomaterials: The Intersection of Biology and Materials Science.[19]

Mikos founded the journals Tissue Engineering Part A, Tissue Engineering Part B: Review, and Tissue Engineering Part C: Methods and currently serves as their editor-in-chief.[4][5][20] He also serves on the editorial boards of multiple other journals including Advanced Drug Delivery Reviews,[21] Cell Transplantation,[22] Journal of Biomaterials Science Polymer Edition,[23] Journal of Biomedical Materials Research (Part A and B),[24] and Journal of Controlled Release[25].[4][5] He has an annual short course on tissue engineering at Rice University since 1993.[4][5][26]

References

  1. ^ "Members of the First Section". Academy of Athens. 23 November 2015. Retrieved 2022-02-03.
  2. ^ "Antonios Mikos". rice.edu. Archived from the original on May 2, 2017. Retrieved May 3, 2017.
  3. ^ "Antonios Mikos". rice.edu. Retrieved May 3, 2017.
  4. ^ a b c d e f g h "Mikos Lab - Principal Investigator". mikoslab.rice.edu. Retrieved 2022-03-29.
  5. ^ a b c d e f g h "Antonios Mikos Rice University Profile". Retrieved March 28, 2022.
  6. ^ a b "Antonios G. Mikos". Purdue University College of Engineering. 2014. Retrieved 29 October 2019.
  7. ^ Kim, Yu Seon; Mehta, Shail M.; Guo, Jason L.; Pearce, Hannah A.; Smith, Brandon T.; Watson, Emma; Koons, Gerry L.; Navara, Adam M.; Lam, Johnny; Grande‐Allen, K. Jane; Mikos, Antonios G. (2021-05-11). "Evaluation of tissue integration of injectable, cell‐laden hydrogels of cocultures of mesenchymal stem cells and articular chondrocytes with an ex vivo cartilage explant model". Biotechnology and Bioengineering. 118 (8): 2958–2966. doi:10.1002/bit.27804. ISSN 0006-3592. PMID 33913514. S2CID 233448399.
  8. ^ Watson, Emma; Tatara, Alexander M.; van den Beucken, Jeroen J.J.P.; Jansen, John A.; Wong, Mark E.; Mikos, Antonios G. (2020-07-01). "An Ovine Model of In Vivo Bioreactor-Based Bone Generation". Tissue Engineering Part C: Methods. 26 (7): 384–396. doi:10.1089/ten.tec.2020.0125. ISSN 1937-3384. PMC 7398437. PMID 32536266.
  9. ^ Smoak, Mollie M.; Han, Albert; Watson, Emma; Kishan, Alysha; Grande-Allen, K. Jane; Cosgriff-Hernandez, Elizabeth; Mikos, Antonios G. (2019-05-01). "Fabrication and Characterization of Electrospun Decellularized Muscle-Derived Scaffolds". Tissue Engineering Part C: Methods. 25 (5): 276–287. doi:10.1089/ten.tec.2018.0339. ISSN 1937-3384. PMC 6535957. PMID 30909819.
  10. ^ Smoak, Mollie M.; Hogan, Katie J.; Grande-Allen, K. Jane; Mikos, Antonios G. (2021-05-14). "Bioinspired electrospun dECM scaffolds guide cell growth and control the formation of myotubes". Science Advances. 7 (20): eabg4123. Bibcode:2021SciA....7.4123S. doi:10.1126/sciadv.abg4123. ISSN 2375-2548. PMC 8121426. PMID 33990336.
  11. ^ Hogan, Katie J.; Smoak, Mollie M.; Koons, Gerry L.; Perez, Marissa R.; Bedell, Matthew L.; Jiang, Emily Y.; Young, Simon; Mikos, Antonios G. (2022-01-06). "Bioinspired electrospun decellularized extracellular matrix scaffolds promote muscle regeneration in a rat skeletal muscle defect model". Journal of Biomedical Materials Research Part A. 110 (5): 1090–1100. doi:10.1002/jbm.a.37355. ISSN 1549-3296. PMID 34989128.
  12. ^ Suggs, Laura J.; Mikos, Antonios G. (July 1999). "Development of Poly(Propylene Fumarate-co-Ethylene Glycol) as an Injectable Carrier for Endothelial Cells". Cell Transplantation. 8 (4): 345–350. doi:10.1177/096368979900800402. ISSN 0963-6897. PMID 10478714. S2CID 36846812.
  13. ^ Habraken, W. J. E. M.; Boerman, O. C.; Wolke, J. G. C.; Mikos, A. G.; Jansen, J. A. (November 2009). "In vitro growth factor release from injectable calcium phosphate cements containing gelatin microspheres". Journal of Biomedical Materials Research Part A. 91A (2): 614–622. doi:10.1002/jbm.a.32263. hdl:2066/80288. PMID 18985784. S2CID 2193015.
  14. ^ Needham, Clark J.; Williams, Austin K.; Chew, Sue Anne; Kasper, F. Kurtis; Mikos, Antonios G. (2012-05-14). "Engineering a Polymeric Gene Delivery Vector Based on Poly(ethylenimine) and Hyaluronic Acid". Biomacromolecules. 13 (5): 1429–1437. doi:10.1021/bm300145q. ISSN 1525-7797. PMC 3351541. PMID 22455481.
  15. ^ Molina, Eric R.; Chim, Letitia K.; Salazar, Maria C.; Koons, Gerry L.; Menegaz, Brian A.; Ruiz-Velasco, Alejandra; Lamhamedi-Cherradi, Salah-Eddine; Vetter, Amelia M.; Satish, Tejus; Cuglievan, Branko; Smoak, Mollie M. (2020-01-13). "3D Tissue-Engineered Tumor Model for Ewing's Sarcoma That Incorporates Bone-like ECM and Mineralization". ACS Biomaterials Science & Engineering. 6 (1): 539–552. doi:10.1021/acsbiomaterials.9b01068. PMID 33463239. S2CID 212993198.
  16. ^ Guo, J. L.; Kim, Y. S.; Xie, V. Y.; Smith, B. T.; Watson, E.; Lam, J.; Pearce, H. A.; Engel, P. S.; Mikos, A. G. (2019-06-07). "Modular, tissue-specific, and biodegradable hydrogel cross-linkers for tissue engineering". Science Advances. 5 (6): eaaw7396. Bibcode:2019SciA....5.7396G. doi:10.1126/sciadv.aaw7396. ISSN 2375-2548. PMC 6551165. PMID 31183408.
  17. ^ Guo, Jason L.; Li, Ang; Kim, Yu Seon; Xie, Virginia Y.; Smith, Brandon T.; Watson, Emma; Bao, Gang; Mikos, Antonios G. (2019-12-13). "Click functionalized, tissue‐specific hydrogels for osteochondral tissue engineering". Journal of Biomedical Materials Research Part A. 108 (3): 684–693. doi:10.1002/jbm.a.36848. ISSN 1549-3296. PMC 7942178. PMID 31755226.
  18. ^ Navara, Adam M.; Kim, Yu Seon; Xu, Yilan; Crafton, Christopher L.; Diba, Mani; Guo, Jason L.; Mikos, Antonios G. (2022-08-01). "A dual-gelling poly(N-isopropylacrylamide)-based ink and thermoreversible poloxamer support bath for high-resolution bioprinting". Bioactive Materials. 14: 302–312. doi:10.1016/j.bioactmat.2021.11.016. ISSN 2452-199X. PMC 8897628. PMID 35310364.
  19. ^ "Biomaterials: The Intersection of Biology and Materials Science". www.pearson.com. Retrieved 2022-03-29.
  20. ^ "Tissue Engineering, Parts A, B, & C | Mary Ann Liebert, Inc., publishers". home.liebertpub.com. Retrieved 2022-03-29.
  21. ^ "Editorial Board - Advanced Drug Delivery Reviews - Journal - Elsevier". www.journals.elsevier.com. Retrieved 2022-03-29.
  22. ^ "Cell Transplantation Editorial Board". Retrieved March 28, 2022.
  23. ^ "Journal of Biomaterials Science, Polymer Edition Editorial Board". www.tandfonline.com. Retrieved 2022-03-29.
  24. ^ "Journal of Biomedical Materials Research Part B: Applied Biomaterials". Wiley Online Library. Retrieved 2022-03-29.
  25. ^ "Editorial Board - Journal of Controlled Release - Journal - Elsevier". www.journals.elsevier.com. Retrieved 2022-03-29.
  26. ^ "Advances in Tissue Engineering Short Course". tissue.rice.edu. Retrieved 2022-03-29.
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