This article may be expanded with text translated from the corresponding article in German. (January 2018) Click [show] for important translation instructions. Machine translation like DeepL or Google Translate is a useful starting point for translations, but translators must revise errors as necessary and confirm that the translation is accurate, rather than simply copy-pasting machine-translated text into the English Wikipedia. Consider adding a topic to this template: there are already 9,701 articles in the main category, and specifying|topic= will aid in categorization. Do not translate text that appears unreliable or low-quality. If possible, verify the text with references provided in the foreign-language article. You must provide copyright attribution in the edit summary accompanying your translation by providing an interlanguage link to the source of your translation. A model attribution edit summary is Content in this edit is translated from the existing German Wikipedia article at [[:de:Bienengift]]; see its history for attribution. You should also add the template ((Translated|de|Bienengift)) to the talk page. For more guidance, see Wikipedia:Translation.

Apitoxin, or honey bee venom, is a cytotoxic and hemotoxic bitter colorless liquid containing proteins, which may produce local inflammation. It may have similarities to sea nettle toxin.[1]


The main component is melittin, amounting to 52% of venom peptides.[2] Adolapin[3] contributes 2–5% of the peptides.[4][5]


Apitoxins are under preliminary research for their potential biological effects, such as in cancer.[6]

See also


  1. ^ Czarnetzki, B. M.; Thiele, T.; Rosenbach, T. (February 1990). "Evidence for leukotrienes in animal venoms". Journal of Allergy and Clinical Immunology. 85 (2): 505–509. doi:10.1016/0091-6749(90)90162-W. PMID 1968071. closed access
  2. ^ Meier J, White J (1995). Clinical toxicology of animal venoms and poisons. CRC Press, Inc. ISBN 0-8493-4489-1.
  3. ^ Aufschnaiter, Andreas; Kohler, Verena; Khalifa, Shaden; Abd El-Wahed, Aida; Du, Ming; El-Seedi, Hesham; Büttner, Sabrina (2020-01-21). "Apitoxin and Its Components against Cancer, Neurodegeneration and Rheumatoid Arthritis: Limitations and Possibilities". Toxins. 12 (2): 66. doi:10.3390/toxins12020066. ISSN 2072-6651. PMC 7076873. PMID 31973181.
  4. ^ "Adolapin". Comparative Toxicogenomics Database, MDI Biological Laboratory and North Carolina State University. 24 August 2017. Retrieved 24 September 2017.
  5. ^ Benton, A. W.; Morse, R. A.; Stewart, J. D. (1963-10-11). "Venom Collection from Honey Bees". Science. 142 (3589): 228–230. Bibcode:1963Sci...142..228B. doi:10.1126/science.142.3589.228. ISSN 0036-8075. PMID 17834840. S2CID 26489746.
  6. ^ Chaisakul, J; Hodgson, W. C; Kuruppu, S; Prasongsook, N (2016). "Effects of Animal Venoms and Toxins on Hallmarks of Cancer". Journal of Cancer. 7 (11): 1571–1578. doi:10.7150/jca.15309. PMC 4964142. PMID 27471574.